Fibrinogen-like protein 2 deficiency inhibits virus-induced fulminant hepatitis through abrogating inflammatory macrophage activation

Table 1 Clinical characteristics of patients and controls

Characteristics	ACLF (n = 7)	Healthy controls (n = 3)
Age (year)	47.14 ± 3.3a	30.33 ± 3.4
Sex (male:female)	6:1	3:0
Laboratory evaluation
ALT (U/L)	642.9 ± 360.3	8.67 ± 1.76
Tbil (μmol/L)	429.8 ± 70.53a	17 ± 2.34
PTA (%)	30.29 ± 3.3a	118 ± 12.17
HBsAg (ng/mL)	3870 ± 1600	0
HBV-DNA (106 copies/mL)	8.18 ± 6.78	0
Ascites and/or Encephalopathy	7	0

^aP < 0.5 vs controls.

Age, Serum alanine aminotransferase, total bilirubin, prothrombin time activity shown as mean ± SD. ACLF: Acute on chronic liver failure; ALT: Alanine aminotransferase; Tbil: Total bilirubin; PTA: Prothrombin time activity.