Effects of microwave ablation on serum Golgi protein 73 in patients with primary liver cancer

doi:10.3748/wjg.v28.i29.3971

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 7, 2022; 28(29): 3971-3980
Published online Aug 7, 2022. doi: 10.3748/wjg.v28.i29.3971

Table 1 Liver biochemical tests in the primary liver cancer patients before and after microwave ablation treatment

	ALB (g/L)	TBIL (μmol/L)	ALT (U/L)	AST (U/L)	GP73 (mg/L)	AFP (mg/L)
Cases	150	150	150	150	150	102¹
Before MWA	42.10 (38.83, 45.20)	16.20 (12.70, 23.35)	30.10 (20.55, 41.55)	28.30 (22.05, 35.40)	90.83 (54.49, 110.60)	110.40 (32.71, 267.30)
1 wk after MWA	38.40 (36.65, 41.15)^a	24.80(16.25, 30.60)^a	102.20(88.65, 166.30)^a	81.70(68.25, 91.30)^a	127.10(84.66, 175.50)^a	37.61(23.30, 95.48)^a
2 wk after MWA	40.30 (38.36, 42.00)	15.00 (12.90, 18.05)	29.40 (25.65, 36.85)	29.00 (24.10, 36.05)	130.70 (88.39, 163.60)	27.34 (6.32, 81.59)^b
4 wk after MWA	43.75 (37.12, 47.31)	17.35 (13.62, 25.76)	33.21 (21.57, 43.82)	26.29 (19.70, 40.61)	102.20 (59.15, 121.90)	7.32 (3.87, 16.25)^c
^at/W	7.037 (t)	3.991 (t)	6.703 (t)	5.768 (t)	5.150 (t)	-157 (W)
^aP	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001

¹Cases with significantly elevated alpha-fetoprotein.

^aP < 0.001 vs before microwave ablation (MWA) as a control.

^bP < 0.001 (W = -190) versus before MWA as a control.

^cP < 0.001 (W = -253) versus before MWA as a control.

t from the paired t-test for normally distributed data and W from the paired Wilcoxon signed-rank test for non-normally distributed data.

MWA: Microwave ablation; ALB: Serum albumin; TBIL: Total bilirubin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; AFP: Alpha-fetoprotein; GP73: Golgi protein 73.

Citation: Xu ZJ, Wei MJ, Zhang XM, Liu HG, Wu JP, Huang JF, Li YF, Huang ZJ, Yan YY. Effects of microwave ablation on serum Golgi protein 73 in patients with primary liver cancer. World J Gastroenterol 2022; 28(29): 3971-3980
URL: https://www.wjgnet.com/1007-9327/full/v28/i29/3971.htm
DOI: https://dx.doi.org/10.3748/wjg.v28.i29.3971