Endoscopic full-thickness resection using an over-the-scope device: A prospective study

Table 1 Patient and lesion characteristics

Patient characteristics (n = 68)
Sex, n (%)
Male	17 (25)
Female	51 (75)
Age, median (range)	52 ± 10.5 (32-71)
Indication for EFTR, n (%)
Submucosal tumor	66 (97.1)
Early cancer	2 (2.9)
Location of lesion, n (%)
Cardia	5 (7.3)
Gastric fundus	41 (60.2)
Gastric body	12 (17.6)
Antrum	6 (8.8)
Duodenum	1 (1.4)
Rectum	4 (4.4)
Maximum diameter of lesion, mean, mm (range)	20, 12.6 ± 4.3 (3-20)

EFTR: Endoscopic full-thickness resection.

Table 2 Procedural data (entire cohort)

Median procedure time, min (range)
Total procedure time	53.7 ± 41.5 (12-263)
EFTR time	39.6 ± 38.0 (5-236)
OTSC defect closure time	5.0 ± 3.8 (2-26)
Technical success, n (%)	68 (100)
R0 resection, n (%)	67 (98.5)

EFTR: Endoscopic full-thickness resection; OTSC: Over-the-scope clip; R0 resection: Histologically complete resection, defined as tumor-free lateral and deep resection margins.

Table 3 Lesion characteristics

Pathological diagnosis, n (%)
GIST	42 (61.7)
Leiomyoma	14 (20.5)
Schwannoma	4 (5.8)
Ectopic pancreas	2 (2.9)
Endometriosis	1 (1.4)
Fibrolipomatous hyperplasia	1 (1.4)
Colorectal adenocarcinoma	2 (2.8)
Inflammatory myofibroblastic tumor like hyperplasia	1 (1.4)
Hyaline degeneration with calcification	1 (1.4)

GIST: Gastrointestinal stromal tumor.

Table 4 Adverse events

Procedure-related adverse events, n (%)
Mild adverse events1
Abdominal pain	18 (26.5)
Discomfort	1 (1.4)
Elevated body temperature	7 (10.3)
Moderate adverse events2
Bleeding	1 (1.5)
Fever	8 (11.8)
Local peritonitis	2 (2.9)
Severe adverse events3	0
Perforation	0
Persistent peritonitis	0

¹Mild adverse events: Not requiring medical or repeated endoscopic intervention and did not prolong hospital admission.

²Moderate adverse events: Requiring medical or repeated endoscopic intervention and/or prolonging hospital admission.

³Severe adverse events: Requiring surgical therapy and/or potentially life threatening.