Serologic diagnosis of celiac disease: May it be suitable for adults?

doi:10.3748/wjg.v27.i42.7233

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Nov 14, 2021 (publication date) through Nov 2, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 14, 2021; 27(42): 7233-7239
Published online Nov 14, 2021. doi: 10.3748/wjg.v27.i42.7233

Table 1 Sensitivity and specificity of serologic tests

Antibody	Sensitivity (range)	Specificity (range)
IgA TGA	98% (78%-100%)	98% (90%-100%)
EMA	95% (86%-100%)	99% (97%-100%)
IgA DGP	88% (74%-100%)	95% (90%-99%)
IgG TGA	70% (45%-95%)	95% (94%-100%)
IgG DGP	80% (63%-95%)	98% (90%-99%)

DGP: Deamidated gliadin antibodies; EMA: Anti-endomysium antibodies; TGA: Anti-transglutaminase antibodies.

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Citation: Losurdo G, Di Leo M, Santamato E, Arena M, Rendina M, Luigiano C, Ierardi E, Di Leo A. Serologic diagnosis of celiac disease: May it be suitable for adults? World J Gastroenterol 2021; 27(42): 7233-7239
URL: https://www.wjgnet.com/1007-9327/full/v27/i42/7233.htm
DOI: https://dx.doi.org/10.3748/wjg.v27.i42.7233