Prophylactic transcatheter arterial embolization reduces rebleeding in non-variceal upper gastrointestinal bleeding: A meta-analysis

Table 1 Basic characteristics of included studies in the systematic review and meta-analysis

Ref.	Country	Study design	Study period	Number of patients/ intervention group	Female %	Age,1 (yr)	Bleeding etiology	Outcome(s)	Embolic agents
Arrayeah et al[27]	United States, Israel	Retrospective cohort	1997–2009	73/56	40	61.1	NVUGIB	Rebleeding, 30-d mortality, reintervention, surgery	Microcoils, gelatin sponge, polyvinyl alcohol particles
Dixon et al[28]	United Kingdom	Retrospective cohort	05.2008–11.2010	27/20	18.5	66	NVUGIB of duodenal origin	Rebleeding, 30-d mortality, reintervention	Microcoils alone or combined with gelatin/gelfoam sponge, polyvinyl alcohol particles
Kaminskis et al[11]	Latvia	Prospective cohort	2014–2018	399/58	44.4	67	High-risk peptic ulcer	Rebleeding, in-hospital mortality, surgery, hospital stay, ICU stay, transfused blood units	ND
Kaminskis et al[12]	Latvia	Prospective cohort	2010–2013	75/25	66.6	64	High-risk peptic ulcer	Rebleeding, in-hospital mortality, surgery, hospital stay, ICU stay, transfused blood units	Coil or sandwich technique
Lau et al[10]	China	Randomized controlled trial	2010–2014	241/118	24.9	66	High-risk peptic ulcer	Rebleeding, 30-d mortality, reintervention, surgery, hospital stay, ICU stay, transfused blood units	Sandwich technique: Coils and gel foam particles
Laursen et al[25]	Denmark	Randomized controlled trial	11.2009–05.2012	105/49	44	73	High-risk peptic ulcer	Rebleeding, in-hospital and 30-d mortality, hospital stay, readmission	Coils
Lebedev et al[29]	Russia	Retrospective cohort	1991–2016	90/30	ND	ND	Peptic ulcer	Rebleeding, mortality	Microcoils, polyvinyl alcohol
Mille et al[30]	Germany	Retrospective cohort	2008–2012	102/55	31.4	70.7	Duodenal ulcer	Rebleeding, 30-d mortality, surgery, transfused blood units	Coils, cyanoacrylate glue or both
Sildiroglu et al[31]	United States	Retrospective cohort	10.2001–11.2011	43/18	ND	60.1	NVUGIB	Rebleeding, mortality	Coils, gelfoam, polyvinyl alcohol
Tong et al[13]	China	Retrospective cohort	2014–2016	74/16	23	57.2	High-risk peptic ulcer	Rebleeding	ND
Wu et al[32]	Australia	Retrospective cohort	01.2008–12.2012	34/8	ND	70.1	Peptic ulcer	Rebleeding	ND
Ying et al[26]	China	Randomized controlled trial	05.2012–06.2013	66/33	25	51.5	Upper GIB	Rebleeding	Gelatin sponge particles
Ying et al[23]	China	Randomized controlled trial	06.2010–06.2014	78/39	46.2	46.5	Upper GIB	Short term haemostasis, long term haemostasis, hospital stay, transfusion	Coils, gelatin sponge
Yonemoto et al[24]	Japan	Retrospective cohort	04.2005–12.2017	141/11	22.7	62.8	Duodenal ulcer	Laboratory data at initial diagnosis, the amount of blood transfusion, 30-d mortality	ND

¹Age is given in mean or median. GIB: Gastrointestinal bleeding, ICU: Intensive care unit, ND: No data, NVUGIB: Non-variceal upper GIB.