Autoimmune enteropathy and primary biliary cholangitis after proctocolectomy for ulcerative colitis: A case report and review of the literature

Table 1 Summary of cases of postcolectomy enteritis from the English databases

Ref.	Age1/sex	Extent of UC	Onset of enteritis2	Extent of enteritis	Histological characteristics of biopsies
Corporaal et al[2]	23/M	Extended left sided	2 wk after colectomy	J, I	Marked apoptosis of epithelial cells, lamina propria with lymphoplasma cellular infiltrate with eosinophilic and neutrophilic granulocytes
Corporaal et al[2]	61/M	Pancolitis	1 mo after colectomy	S, D, J, I	Diffuse active chronic inflammatory infiltrate with (sub) total villous atrophy (D), an increase in the apoptosis of crypt epithelial cells (I), and dense active chronic inflammation (S)
Gooding et al[14]	52/M	Pancolitis	116 d after colectomy	D, I	Infiltration of the lamina propria by lymphocytes, plasma cells, and neutrophils; cryptitis and small numbers of neutrophils within the upper-crypt lamina and on the surface (D); shortening and irregularity of villi; mild, diffuse, chronic inflammatory cell infiltration; and mild activity with cryptitis (I)
Ikeuchi et al[15]	29/F	Left sided	6 yr after colectomy	S, D, I	Severe infiltration of inflammatory cells in the mucosa (I, S) and crypt abscess in the mucous glandules (S), dense, acute, and chronic inflammatory infiltrates accompanied with cryptitis (D)
Kawai et al[16]	Young (unknown)/M	Pancolitis	12 yr after colectomy	D	Lymphoplasmacytic infiltration of the duodenal mucosa without granuloma formation
Kawai et al[16]	Unknown/M	Unknown	2 yr after colectomy	I	Unknown
Rubenstein et al[17]	38/M	Pancolitis	Immediately after colectomy	D, J, I	Diffuse mucosal inflammation with the distortion of the crypt architecture and plasmacytosis
Nakayama et al[18]	41/M	Pancolitis	3.5 yr after colectomy	D, I	Inflammatory infiltration by neutrophils, eosinophils, lymphocytes, and plasma cells
Terashima et al[19]	30/M	Left sided	7 mo after colectomy, immediately after closure of ileostoma	D	Severe lymphoplasmacytic infiltration withcryptitis
Valdez et al[20]	5/F	Pancolitis	17 mo after colectomy	D	Diffuse mucosal inflammation, cryptitis, and architectural distortion
Valdez et al[20]	17/F	Pancolitis	9 mo after colectomy	D, I	Diffuse mucosal inflammation, cryptitis, and architectural distortion
Valdez et al[20]	58/F	Pancolitis	6 mo after colectomy	D, J	Typical microscopic features of UC (no other details)
Valdez et al[20]	17/M	Pancolitis	8 d after colectomy	D, I	UC-like active, diffuse duodenitis and ileitis (no other details)
Annese et al[21]	37/M	Pancolitis	1 mo after colectomy	D, J, I	Architectural disarray and dense inflammatory infiltrate extending beyond the muscularis mucosae, mainly comprised of plasma cells and lymphocytes (D, J). Distorted villi and a heavily inflamed lamina propria with mononuclear cell inflammatory infiltrate (I)
Feuerstein et al[4]	56/F	Left sided	26 d after colectomy	D, J, I	Severe, active enteritis with ulceration and prominent epithelial cell, apoptotic debris
Nakajima et al[5]	25/F	Pancolitis	Immediately after colectomy	D, J, I	Infiltration of inflammatory cells in the mucosa and decreased goblet cells
Hoentjen et al[22]	23/M	Pancolitis	3 mo after colectomy	S, D, I	Severe active inflammation with significant neutrophil infiltration in the epithelium and lamina propria
Hoentjen et al[22]	24/F	Pancolitis	4 mo after colectomy	S, D, I	Mixed cell infiltrates in the lamina propria, including a prominent component of plasma cells and clusters of neutrophils, negative for crypt cell apoptosis and decreased goblet cells
Hoentjen et al[22]	27/M	Pancolitis	25 yr after colectomy	S, D, I	Active inflammation with prominent eosinophils in the lamina propria (S, D) and remarkable architectural distortion (I)
Hoentjen et al[22]	57/M	Pancolitis	27 mo after colectomy	S, D, I	Diffuse and active Helicobacter pylori-negative gastritis, duodenitis and ileitis (no other details)
Uchino et al[23]	19/M	Pancolitis	12 d after colectomy	S, D, I	Neutrophil infiltration and crypt abscess
Rush et al[24]	43/F	Pancolitis	3 mo after colectomy	S, D, J, I	Moderate to marked active chronic inflammation with cryptitis
Rosenfeld et al[25]	47/F	Pancolitis	4 mo after colectomy	D, J	Moderate to severe active inflammatory changes in the small bowel mucosa with cryptitis

¹Age at the onset of postcolectomy enteritis.

²Interval between colectomy and the onset of enteritis symptoms. S: Stomach; D: Duodenum; J: Jejunum; I: Ileum; UC: Ulcerative colitis; F: Female; M: Male.