Copyright
©The Author(s) 2020.
World J Gastroenterol. Sep 14, 2020; 26(34): 5207-5219
Published online Sep 14, 2020. doi: 10.3748/wjg.v26.i34.5207
Published online Sep 14, 2020. doi: 10.3748/wjg.v26.i34.5207
Table 1 Description of 16 studies included in the final analysis
| Ref. | Year | Type of study | Center | Mean age (yr) | No. of patients | Males | Females | ||
| Total | EHL | LL | Total | Total | |||||
| Howell et al[29] | 1999 | Prospective | Single | 62.5 | 6 | 6 | 0 | 5 | 1 |
| Hirai et al[28] | 2004 | Prospective | Single | 51.2 | 17 | 0 | 17 | 9 | 8 |
| Brauer et al[30] | 2007 | Prospective | Single | 54 | 27 | 27 | 0 | 12 | 15 |
| Chen et al[8] | 2008 | Prospective | Single | -- | 10 | 10 | 0 | -- | -- |
| Fishman et al[9] | 2009 | Retrospective | Multi | -- | 6 | 6 | 0 | -- | -- |
| Maydeo et al[27] | 2011 | Prospective | Single | -- | 4 | 0 | 4 | -- | -- |
| Shah et al[26] | 2012 | Retrospective | Multi | 51 | 28 | 0 | 28 | -- | -- |
| Alatawi et al[31] | 2013 | Prospective | Single | 53.8 | 5 | 0 | 5 | 4 | 1 |
| Ito et al[23] | 2014 | Prospective | Single | -- | 8 | 8 | 0 | -- | -- |
| Malachias et al[24] | 2017 | Retrospective | Single | -- | 19 | 0 | 19 | 13 | 6 |
| Bekkali et al[7] | 2017 | Retrospective | Single | 45 | 6 | 6 | 0 | 3 | 3 |
| Canena et al[20] | 2019 | Prospective | Multi | -- | 3 | 2 | 1 | 3 | 0 |
| Gerges et al[21] | 2019 | Retrospective | Multi | 62.4 | 20 | 2 | 18 | 11 | 9 |
| Brewer Gutierrez et al[2] | 2019 | Retrospective | Multi | 54.7 | 109 | 59 | 50 | 77 | 32 |
| Ogura et al[25] | 2019 | Prospective | Single | 55 | 21 | 21 | 0 | 15 | 6 |
| Han et al[22] | 2019 | Retrospective | Single | -- | 94 | -- | -- | -- | -- |
Table 2 Pooled rates of technical success, clinical success, and adverse events of per oral pancreatoscopy, electrohydraulic lithotripsy and laser lithotripsy
| POP (%) | EHL (%) | LL (%) | |
| Technical success | 76.4 (95%CI: 65.9-84.5; I2 = 64%) | 70.3 (95%CI: 57.8-80.3; I2 = 36%) | 89.3 (95%CI: 70.5-96.7; I2 = 70%) |
| Clinical success | 76.8 (95%CI: 65.2-85.4; I2 = 66%) | 66.5 (95%CI: 55.2-76.2; I2 = 19%) | 88.2 (95%CI: 66.4-96.6; I2 = 77%) |
| All adverse events | 14.9 (95%CI: 9.2-23.2; I2 = 49%) | 11.2 (95%CI: 5.9-20.3; I2 = 15%) | 13.1 (95%CI: 6.3-25.4; I2 = 31%) |
| PEP | 7.0 (95%CI: 3.5-13.6; I2 = 38%) | -- | -- |
| Fever | 3.7 (95%CI: 2-6.9; I2 = 0) | -- | -- |
| Abdominal pain | 4.7 (95%CI: 2.7-7.8; I2 = 0) | -- | -- |
| Perforation | 4.3 (95%CI: 2.1-8.4; I2 = 0) | -- | -- |
| Hemorrhage | 3.4 (95%CI: 1.7-6.6; I2 = 0) | -- | -- |
Table 3 Adverse events in all procedures
| Ref. | Total | PEP | Perforation | Bleeding | Fever | Abd pain | EHL | LL |
| Howell et al[29] | 2 | 0 | 1 | 0 | 0 | 1 | 2 | 0 |
| Hirai et al[28] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Brauer et al[30] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Chen et al[8] | 1 | -- | -- | -- | -- | -- | 1 | -- |
| Fishman et al[9] | -- | -- | -- | -- | -- | -- | -- | -- |
| Maydeo et al[27] | -- | -- | -- | -- | -- | -- | -- | -- |
| Shah et al[26] | 7 | -- | -- | -- | -- | -- | 0 | 7 |
| Alatawi et al[31] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Ito et al[23] | 2 | 1 | 1 | 0 | 0 | 0 | 2 | 0 |
| Malachias et al[24] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Bekkali et al[7] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -- |
| Canena et al[20] | 2 | 1 | 0 | 0 | 1 | 0 | -- | -- |
| Gerges et al[21] | 7 | 5 | 1 | 1 | 0 | 0 | -- | -- |
| Brewer Gutierrez et al[2] | 14 | 5 | 1 | 2 | 3 | 3 | 5 | 6 |
| Ogura et al[25] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
| Han et al[22] | 8 | 1 | 0 | 0 | 1 | 5 | 7 | 1 |
- Citation: Saghir SM, Mashiana HS, Mohan BP, Dhindsa BS, Dhaliwal A, Chandan S, Bhogal N, Bhat I, Singh S, Adler DG. Efficacy of pancreatoscopy for pancreatic duct stones: A systematic review and meta-analysis. World J Gastroenterol 2020; 26(34): 5207-5219
- URL: https://www.wjgnet.com/1007-9327/full/v26/i34/5207.htm
- DOI: https://dx.doi.org/10.3748/wjg.v26.i34.5207