Acceptance on colorectal cancer screening upper age limit in South Korea

Table 1 Baseline characteristics of the study participants

Variables	Total (n = 1922)	Stop CRC screening at 80 years
		No (n = 368)	Yes (n = 1554)	P value
Age group
50-59	1025 (53.3)	192 (52.2)	833 (53.6)	0.002
60-69	675 (35.1)	115 (31.3)	560 (36.0)
70-74	222 (11.6)	61 (16.6)	161 (10.4)
Sex
Male	927 (48.2)	153 (41.6)	774 (49.8)	0.004
Female	995 (51.8)	215 (58.4)	780 (50.2)
Residential region
Rural	259 (13.5)	68 (18.5)	191 (12.3)	< 0.0001
Urban	779 (40.5)	170 (46.2)	629 (40.5)
Metropolitan	864 (45.0)	130 (35.3)	734 (47.2)
Education
No formal/Elementary school	155 (8.1)	52 (14.1)	103 (6.6)	< 0.0001
Middle/High school	1421 (73.9)	249 (67.7)	1172 (75.4)
College or more	346 (18.0)	67 (18.2)	279 (18)
Occupation status
Employed	1258 (65.5)	240 (65.2)	1018 (65.5)	0.916
Unemployed/Housewife	664 (34.6)	128 (34.8)	536 (34.5)
Household monthly income (USD)
< 3000	614 (32)	135 (36.7)	479 (30.8)	0.077
3000-5000	955 (49.7)	166 (45.1)	789 (50.8)
> 5000	353 (18.4)	67 (18.2)	286 (18.4)
Marital status
Living without spouse	102 (5.3)	28 (7.6)	74 (4.8)	0.028
Living with spouse	1820 (94.7)	340 (92.4)	1480 (95.2)
CRC screening experience
Never	504 (26.2)	45 (12.2)	459 (29.5)	< 0.0001
FOBT only	688 (35.8)	144 (39.1)	544 (35.0)
Colonoscopy only	299 (15.6)	62 (16.9)	237 (15.3)
Both FOBT and colonoscopy	431 (22.4)	117 (31.8)	314 (20.2)
Other type of cancer screening in NCSP
No	337 (17.5)	27 (7.3)	310 (20.0)	< 0.0001
Yes	1585 (82.5)	341 (92.7)	1244 (80.1)
Family history of cancer
No	1508 (78.5)	263 (71.5)	1245 (80.1)	< 0.0001
Yes	414 (21.5)	105 (28.5)	309 (19.9)
Lifetime smoking
Never or < 5 packs	1224 (63.7)	259 (70.4)	965 (62.1)	0.003
More than 5 packs	698 (36.3)	109 (29.6)	589 (37.9)
Drinking within 1 yr
Never	499 (26.0)	115 (31.3)	384 (24.7)	0.036
Sometime	1022 (53.2)	183 (49.7)	839 (54.0)
Frequently	401 (20.9)	70 (19.0)	331 (21.3)
Exercise
Never	1044 (54.3)	223 (60.6)	821 (52.8)	0.02
1-2 d per week	336 (17.5)	51 (13.9)	285 (18.3)
> 3 d per week	542 (28.2)	94 (25.5)	448 (28.8)

CRC: Colorectal cancer; FOBT: Fecal occult blood test; NCSP: National Cancer Screening Program.

Table 2 Logistic regression for factors associated with acceptance of an upper age limit for colorectal cancer screening at 80 years (n = 1992)

Variable	Stop CRC screening at 80 yr
	Univariate		Multivariate
	cOR	95%CI	aOR	95%CI
Age group
50-59	1.00		1.00
60-69	1.12	0.87-1.45	1.22	0.92-1.64
70-74	0.61	0.44-0.85	0.72	0.47-1.11
Sex
Male	1.00		1.00
Female	0.72	0.57-0.9	0.86	0.59-1.24
Residential region
Rural	1.00		1.00
Urban	1.32	0.95-1.82	1.34	0.95-1.91
Metropolitan	2.01	1.44-2.81	1.86	1.29-2.68
Education
No formal/Elementary school	1.00		1.00
Middle/High school	2.38	1.66-3.41	1.55	1.00-2.39
College or more	2.10	1.37-3.22	1.28	0.74-2.21
Occupation status
Employed	1.00
Unemployed/Housewife	0.99	0.78-1.25
Household monthly income (USD)
< 3000	1.00		1.00
3000-5000	1.34	1.04-1.73	1.04	0.76-1.42
> 5000	1.20	0.87-1.67	0.97	0.64-1.47
Marital status
Living without spouse	1.00		1.00
Living with spouse	1.65	1.05-2.58	1.21	0.74-1.98
CRC screening experiences
Never	1.00		1.00
FOBT only	0.37	0.26-0.53	0.50	0.34-0.75
Colonoscopy only	0.37	0.25-0.57	0.49	0.31-0.77
Both FOBT and colonoscopy	0.26	0.18-0.38	0.33	0.22-0.50
Other type of cancer screening in NCSP
No	1.00		1.00
Yes	0.32	0.21-0.48	0.55	0.34-0.87
Family history of cancer
No	1.00		1.00
Yes	0.62	0.48-0.80	0.66	0.50-0.87
Lifetime smoking
Never or < 5 packs	1.00		1.00
More than 5 packs	1.45	1.13-1.86	1.38	0.95-2.02
Drinking within 1 yr
Never	1.00		1.00
Sometime	1.37	1.06-1.79	1.06	0.79-1.41
Frequently	1.42	1.02-1.97	0.87	0.59-1.3
Exercise
Never	1.00		1.00
1-2 d per week	1.52	1.09-2.12	1.37	0.97-1.95
> 3 d per week	1.29	0.99-1.69	1.42	1.07-1.89

cOR: Crude odds ratio; aOR: Adjusted odds ratio; CRC: Colorectal cancer; FOBT: Fecal occult blood test; NCSP: National Cancer Screening Program.

Table 3 Logistic regression for acceptance of an upper age limit for colorectal cancer screening at 80 years according to colorectal cancer screening history (n = 1992)

Variable	Stop CRC screening at 80 yr
	Never-screened (n = 504)		Ever-screened (n = 1418)
	aOR	95%CI	aOR	95%CI
Age group
50-59	1.00		1.00
60-69	1.46	0.62-3.42	1.16	0.85-1.59
70-74	0.60	0.22-1.66	0.71	0.44-1.13
Sex
Male	1.00		1.00
Female	0.25	0.08-0.82	1.07	0.72-1.59
Residential region
Rural	1.00		1.00
Urban	2.25	0.69-7.34	1.21	0.84-1.75
Metropolitan	2.95	0.85-10.21	1.80	1.23-2.65
Education
No formal/Elementary school	1.00	1.00	1.00
Middle/High school	0.86	0.14-5.17	1.56	1.00-2.46
College or more	0.66	0.09-4.86	1.37	0.76-2.45
Household monthly income (USD)
< 3000	1.00		1.00
3000-5000	1.51	0.6-3.84	0.95	0.68-1.32
> 5000	0.77	0.25-2.36	0.98	0.63-1.54
Marital status
Living without spouse	1.00		1.00
Living with spouse	3.71	1.10-12.48	1.02	0.60-1.76
Other type of cancer screening in NCSP
No	1.00		1.00
Yes	0.81	0.39-1.66	0.56	0.29-1.05
Family history of cancer
No	1.00		1.00
Yes	0.90	0.36-2.25	0.61	0.46-0.82
Lifetime smoking
Never or < 5 packs	1.00		1.00
More than 5 packs	7.10	1.24-40.61	1.33	0.89-1.99
Drinking within 1 yr
Never	1.00		1.00
Sometime	0.72	0.3-1.75	1.14	0.83-1.55
Frequently	0.31	0.09-1.02	0.98	0.64-1.50
Exercise
Never	1.00		1.00
1-2 d per week	0.83	0.34-2.02	1.50	1.02-2.20
> 3 d per week	0.87	0.37-2.04	1.49	1.10-2.02

aOR: Adjusted odds ratio; CRC: Colorectal cancer; NCSP: National Cancer Screening Program.