Landscape of BRIP1 molecular lesions in gastrointestinal cancers from published genomic studies

Table 1 Likely oncogenic BRIP1 mutations in gastrointestinal cancers according to the OncoKB database

Sample ID	Cancer type	Protein change	Mutation type	Copy number	Allele frequency	Number of mutations	Exon
TCGA-A6-3807-01	Colon adenocarcinoma	S1117*	Nonsense_muta-tion	Diploid	0.21	90	20
TCGA-DT-5265-01	Rectal adenocarcinoma	Q227*	Nonsense_muta-tion	Shallow del	0.59	81	7
TCGA-AA-3496-01	Colon adenocarcinoma	I504Nfs*7	Frame_Shift_Ins	Gain	0.43	145	11
TCGA-AZ-4315-01	Colon adenocarcinoma	E357*	Nonsense_muta-tion	Diploid	0.32	6317	8
TCGA-L5-A4OE-01	Esophageal adenocarcinoma	Q126*	Nonsense_muta-tion	Gain	0.35	267	4
TCGA-CG-5721-01	Gastric adenocarcinoma	I504Sfs*22	Frame_Shift_Del	Diploid	0.22	3725	11

The column “Number of mutations” presents the total number of mutations in the respective sample. Ins: Insertion; Del: Deletion.