Metabolic syndrome attenuates ulcerative colitis: Correlation with interleukin-10 and galectin-3 expression

Table 1 Clinical and laboratory findings in ulcerative colitis patients

Characteristics	All (n = 89)	Without MetS (n = 17)	With MetS (n = 72)	P value
Age (yr)
Median (range)	50 (21-80)	34 (23-54)	53 (21-80)	0.001
Gender, n (%)
Male	52 (58.43)	11 (64.71)	41 (56.95)	> 0.05
Female	37 (41.57)	6 (35.29)	31 (43.05)
Smoking status, n (%)
Yes	42 (47.19)	7 (41.18)	35 (48.61)	> 0.05
No	47 (52.81)	10 (58.82)	37 (51.39)
Localization (PT/LC/PC)	13/51/25	3/7/7	10/44/18	> 0.05
Extraintestinal manifestations (+/-)	34/55	7/10	27/45	> 0.05
WBC (109/L)	8.18 ± 0.48	10.27 ± 1.04	7.69 ± 0.49	0.025
Platelet (109/L)	377.2 ± 11.4	400.80 ± 28.10	371.60 ± 11.60	> 0.05
Hb (g/L)	125.7 ± 1.97	120.90 ± 4.10	126.80 ± 2.10	> 0.05
Cholesterol (mmol/L)	4.91 ± 0.18	3.71 ± 0.21	5.19 ± 0.19	0.001
Triglycerides (mmol/L)	1.63 ± 0.11	0.89 ± 0.07	1.81 ± 0.11	0.001
HDL (mmol/L)	1.54 ± 0.07	1.73 ± 0.14	1.50 ± 0.07	> 0.05
LDL (mmol/L)	2.62 ± 0.18	1.49 ± 0.28	2.89 ± 0.19	0.001
AST (U/L)	30.08 ± 1.87	20.65 ± 2.27	32.31 ± 2.07	0.002
ALT (U/L)	33.19 ± 4.50	23.29 ± 2.24	35.53 ± 5.28	0.039
GGT (U/L)	36.00 ± 6.70	20.94 ± 2.51	39.56 ± 7.88	> 0.05
Urea (mmol/L)	5.13 ± 0.30	3.69 ± 0.43	5.47 ± 0.33	0.014
Creatinine (µmol/L)	81.89 ± 2.79	68.71 ± 3.31	85.00 ± 3.09	0.014
Albumin (g/L)	41.33 ± 0.88	41.88 ± 0.88	41.19 ± 0.40	> 0.05
Globulin (g/L)	27.44 ± 0.37	27.82 ± 0.59	27.35 ± 0.42	> 0.05

Values are expressed as mean ± standard error of the mean. PT: Proctitis; LC: Left-sided colitis; PC: Pancolitis; MetS: Metabolic syndrome; WBC: White blood cells count; Hb: Hemoglobin; HDL: High-density lipoprotein; LDL: Low-density lipoprotein; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; GGT: Gamma-glutamyl transpeptidase.