©The Author(s) 2019.
World J Gastroenterol. Oct 14, 2019; 25(38): 5838-5849
Published online Oct 14, 2019. doi: 10.3748/wjg.v25.i38.5838
Published online Oct 14, 2019. doi: 10.3748/wjg.v25.i38.5838
Table 1 Patient, operation, tumor, and postoperative characteristics
| Characteristic | Category | n = 162 | Percentage (%) |
| Sex | Female | 38 | 23.46 |
| Male | 124 | 76.54 | |
| Age(yr) | Range 30-89 | — | — |
| Mean 59.5, median 59.0 | — | — | |
| BMI (kg/m2) | Range 22.30-26.80 | — | — |
| Mean 24.66, median 24.95 | — | — | |
| Previous abdominal surgery | No | 131 | 80.86 |
| Yes | 31 | 19.14 | |
| Operation method | Open surgery | 63 | 38.89 |
| Laparoscopic surgery | 99 | 61.11 | |
| Operation time (min) | Range 120-433 | — | — |
| Mean 236.4, median 230.0 | — | — | |
| Intraoperative blood loss (mL) | Range 10-1800 | — | — |
| Mean 229.4, median 200.0 | — | — | |
| Blood transfusion | No | 131 | 80.86 |
| Yes | 31 | 19.14 | |
| Surgical procedure | Proximal gastrectomy | 21 | 12.96 |
| Distal gastrectomy | 56 | 34.57 | |
| Total gastrectomy | 85 | 52.47 | |
| Lymph node dissection | D1+ | 40 | 24.69 |
| D2 | 122 | 75.31 | |
| Tumor stage | I | 39 | 24.07 |
| II | 50 | 30.86 | |
| III | 72 | 44.44 | |
| IV | 1 | 0.62 | |
| Postoperative body temperature (°C) | Range 36.4-39.1 | — | — |
| Mean 37.6, median 37.5 | — | — | |
| Postoperative WBC count (×109/L) | Range 5.43-22.02 | — | — |
| Mean 12.76, median 12.70 | — | — | |
| Postoperative albumin (g/L) | Range 25.5-40.3 | — | — |
| Mean 31.93, median 31.80 | — | — | |
| Postoperative K+ (mmol/L) | Range 2.67-5.15 | — | — |
| Mean 3.75, median 3.74 | — | — | |
| Postoperative opioid analgesic | No | 100 | 61.73 |
| Yes | 62 | 38.27 | |
| PPOI | No | 130 | 80.25 |
| Yes | 32 | 19.75 |
Table 2 Association of prolonged postoperative ileus with background, operative, and postoperative variables in bivariate analysis and in multivariable models
| Variable | Category | Number (%) with PPOI | Univariate OR(95%CI) | P value | Multivariable OR (95%CI) | P value |
| Sex | Female | 9/38 (23.7) | 1.36 (0.57, 3.27) | 0.487 | — | — |
| Male | 23/124 (18.5) | Ref. | — | — | — | |
| Age (yr) | Continuous variable | — | 1.05 (1.01, 1.09) | 0.009 | — | — |
| ≤ 60 | 12/88 (13.6) | 0.43 (0.19, 0.95) | 0.033 | Ref. | 0.030 | |
| > 60 | 20/74 (27.0) | Ref. | — | 2.70 (1.10, 6.66) | — | |
| BMI (kg/m2) | Continuous variable | — | 0.91 (0.81, 1.02) | 0.110 | — | — |
| ≤ 24.66 | 17/78 (21.8) | 1.02 (0.42, 2.49) | 0.529 | — | — | |
| > 24.66 | 15/84 (17.9) | Ref. | — | — | — | |
| Previous abdominal surgery | No | 27/131 (15.1) | 1.35 (0.47, 3.85) | 0.573 | — | — |
| Yes | 5/31 (16.1) | Ref. | — | — | — | |
| Operation method | Open surgery | 18/63 (20.6) | 2.44 (1.11, 5.26) | 0.025 | 3.45 (1.33, 9.09) | — |
| Laparoscopic surgery | 14/99 (14.1) | Ref. | — | Ref. | 0.010 | |
| Operation time (min) | Continuous variable | — | 0.99 (0.99, 1.00) | 0.532 | — | — |
| ≤ 236.4 | 16/89 (18.0) | 0.78 (0.36, 1.69) | 0.531 | — | — | |
| > 236.4 | 16/73 (21.9) | Ref. | — | — | — | |
| Intraoperative blood loss (mL) | Continuous variable | — | 1.00 (0.99, 1.00) | 0.693 | — | — |
| ≤ 229.4 | 16/87 (18.4) | 1.02 (0.42, 2.49) | 0.639 | — | — | |
| > 229.4 | 8/75 (21.3) | Ref. | — | — | — | |
| Blood transfusion | No | 23/131 (17.6) | 0.52 (0.21, 1.28) | 0.149 | — | — |
| Yes | 9/31 (29.0) | Ref. | — | — | — | |
| Surgical procedure | Total gastrectomy | 21/85 (24.7) | Ref. | — | — | — |
| Proximal gastrectomy | 3/21(14.3) | 0.51 (0.14, 1.89) | 0.314 | — | — | |
| Distal gastrectomy | 8/56 (14.3) | 0.51 (0.21, 1.25) | 0.138 | — | — | |
| lymph node dissection | D1+ | 5/40 (12.5) | Ref. | — | — | — |
| D2 | 27122 (22.1) | 1.99 (0.71, 5.59) | 0.191 | — | — | |
| Tumor stage | I-II | 12/89 (13.5) | 0.41 (0.19, 0.92) | 0.027 | Ref. | 0.010 |
| III-IV | 20/73 (27.4) | Ref. | — | 3.23 (1.32, 7.90) | — | |
| Postoperative body temperature (°C) | Continuous variable | — | 0.99 (0.47, 2.05) | 0.969 | — | — |
| ≤ 37.6 | 19/97 (19.6) | 0.97 (0.44, 2.14) | 0.948 | — | — | |
| > 37.6 | 13/65 (20.0) | Ref. | — | — | — | |
| Postoperative WBC count (×109/L) | Continuous variable | — | 1.04 (0.92, 1.17) | 0.572 | — | — |
| ≤ 12.76 | 18/82 (22.0) | 1.33 (0.61, 2.89) | 0.477 | — | — | |
| > 12.76 | 14/80 (17.5) | Ref. | — | — | — | |
| Postoperative albumin (g/L) | Continuous variable | — | 0.83 (0.72, 0.95) | 0.007 | — | — |
| ≤ 31.93 | 21/86 (24.4) | 1.91 (0.85, 4.28) | 0.113 | — | — | |
| > 31.93 | 11/76 (14.5) | Ref. | — | — | — | |
| Postoperative K+ (mmol/L) | Continuous variable | — | 0.26 (0.08, 0.81) | 0.020 | — | — |
| ≤ 3.75 | 20/85 (23.5) | 1.67 (0.75, 3.69) | 0.205 | — | — | |
| > 3.75 | 12/77 (16.0) | Ref. | — | — | — | |
| Postoperative opioid analgesic | No | 12/100 (12.0) | 0.29 (0.13, 0.64) | 0.002 | Ref. | < 0.001 |
| Yes | 20/62 (32.3) | Ref. | — | 5.84 (2.25, 15.16) | — | |
| Postoperative opioid analgesic | No | 12/100 (12.0) | 0.002 | 0.29 (0.13, 0.64) | — |
- Citation: Liang WQ, Zhang KC, Cui JX, Xi HQ, Cai AZ, Li JY, Liu YH, Liu J, Zhang W, Wang PP, Wei B, Chen L. Nomogram to predict prolonged postoperative ileus after gastrectomy in gastric cancer. World J Gastroenterol 2019; 25(38): 5838-5849
- URL: https://www.wjgnet.com/1007-9327/full/v25/i38/5838.htm
- DOI: https://dx.doi.org/10.3748/wjg.v25.i38.5838