Autoimmune hepatitis and IgG4-related disease

Table 1 Autoimmune hepatitis and IgG4-associated autoimmune hepatitis

Ref.	Chunget al[7]	Umemuraet al[8]	Amarapurkar et al[9]	Canivetet al[10]	Aydemir et al[11]
Country	Japan	Japan	India	France	Turkey
Number of AIH	26 adults	60 adults	40 adults	28 adults	40 children
Number of IgG4-AIH	9 (34.6%)	2 (3.3 %)	10 (25.0%)	7 (25.0%)	6 (15.0%)
Diagnostic criteria for IgG4-AIH	> 5 IgG4+ cells/HPF	> 10 IgG4+ cells/HPF	> 5 IgG4+ cells/HPF	> 10 IgG4+ cells/HPF	> 10 IgG4+ cells/HPF
Laboratory findings vs cAIH
ALT	No difference	No difference	No difference	No difference	No difference
ALP	No difference	No difference	No difference	No difference	NA
γGTP	No difference	NA	NA	No difference	No difference
IgG	Higher	No difference	NA	Higher	No difference
IgG4	No difference	Higher	Higher	NA	NA
Presence of ANA	No difference	No difference	NA	No difference	NA
Detection rate of pathological findings vs cAIH
Portal inflammation	No difference	No difference	NA	NA	No difference
Interface hepatitis	No difference	Higher	NA	NA	No difference
Lobular hepatitis	Higher	Higher	NA	NA	NA
Plasma cell infiltration	Higher	Higher	NA	NA	No difference
Eosinophil infiltration	Not detected	No difference	NA	NA	No difference
Rosette formation	Higher	Higher	NA	No difference	No difference
Bile duct damage	No difference	Lower	NA	NA	NA
Degree of Fibrosis vs cAIH	No difference	NA	No difference	No difference	No difference
IAIHG score vs cAIH	Higher	No difference	No difference	NA	No difference
ALT normalization time after PSL therapy vs cAIH	Shorter	NA	NA	NA	Shorter

cAIH: Classical autoimmune hepatitis; HPF: High-powered field; NA: Not available; IAIHG: International autoimmune hepatitis group; PSL: Prednisolone.