Short hairpin RNA-mediated knockdown of nuclear factor erythroid 2-like 3 exhibits tumor-suppressing effects in hepatocellular carcinoma cells

Table 1 Association of nuclear factor erythroid 2-like 3 expression with clinicopathological features of hepatocellular carcinoma patients in The Cancer Genome Atlas dataset n (%)

Variable	NFE2L3 expression		Total cases	P-value
	Low (n = 172)	High (n = 172)
Tumor grade				0.0006
G1/2	122 (70.9)	91 (52.9)	213
G3/4	50 (29.1)	81 (47.1)	131
T stage				0.0070
T1	100 (58.1)	71 (41.2)	171
T2	35 (20.3)	52 (30.2)	87
T3/4	37 (21.5)	49 (28.5)	86
Pathologic stage				0.0138
I	98 (57.0)	71 (41.2)	169
II	35 (20.3)	50 (29.1)	85
III/IV	39 (22.7)	51 (29.7)	90

NFE2L3: Nuclear factor erythroid 2-like 3.

Table 2 Pearson correlation coefficients for the relationship of nuclear factor erythroid 2-like 3 expression and clinicopathological features

	NFE2L3 expression		Tumor grade		T stage		Pathologic stage
	r	P-value	r	P-value	r	P-value	r	P-value
NFE2L3 expression	1.000		0.2354	< 0.0001	0.1913	0.0004	0.1811	0.0007
Tumor grade	0.2354	< 0.0001	1.000		-0.0032	0.9522	-0.0069	0.8985
T stage	0.1913	0.0004	-0.0032	0.9522	1.000		0.9814	< 0.0001
Pathologic stage	0.1811	0.0007	-0.0069	0.8985	0.9814	< 0.0001	1.000

NFE2L3: Nuclear factor erythroid 2-like 3.