Emodin and baicalein inhibit sodium taurocholate-induced vacuole formation in pancreatic acinar cells

Table 1 Criteria for microscopic assessment

Histological pattern	Assessment	Score
Edema	Mild	1
	Moderate	2
	Severe	3
Inflammatory infiltration	Mild	1
	Moderate	2
	Severe	3
Fat necrosis	< 2/section	3
	3-5/section	5
	> 5/section	7
Parenchymal necrosis	Focal (< 5%)	3
	And/or sublobular (< 20%)	5
	And/or lobular (> 20%)	7
Hemorrhage	Mild	3
	Moderate	5
	Severe	7

Table 2 The duration of cells sustained at high calcium concentration

Group	Duration of cells sustained at high calcium concentration (s)
Control	0 ± 0.03
SAP	30 ± 1.77a
CEB	5 ± 1.80c

^aP < 0.05 vs control group;

^cP < 0.05 vs SAP group. SAP: Severe acute pancreatitis; CEB: Combined use of emodin and baicalein.