Suppression of colorectal tumorigenesis by recombinant Bacteroides fragilis enterotoxin-2 in vivo

Table 1 Comparison of the average lengths of the large intestine, the numbers of tumors and the diameters of tumors of mice from each group

	BC group	AD group	ADLT group	ADHT group
Length of the large intestine, cm	8.90 ± 0.10	8.10 ± 0.401	8.27 ± 0.311	8.20 ± 0.101
Number of tumors	-	19.75 ± 3.30	6.50 ± 1.732	6.00 ± 2.162
Diameter of tumors, mm	-	1.72 ± 0.40	1.15 ± 0.413	1.07 ± 0.403

¹Represents a statistical significance in the length of the large intestine when compared between the BC group and the AD group or the ADLT group or the ADHT group (P < 0.05, respectively);

²Represents that the number of tumors in the AD group was statistically different from those in the ADLT group and the ADHT group (P < 0.05, respectively);

³Represents that the average diameter of tumors in the AD group was statistically different from those in the ADLT group and the ADHT group (P < 0.05, respectively).

Table 2 Expression of Ki-67 and Caspase-3 of mice from each group

Group	n	Ki-67		Caspase-3
		-	+	-	+
BC	10	8 (80.00)	2 (20.00)	3 (30.00)	7 (70.00)
AD	18	1 (5.56)	17 (94.44)1	15 (83.33)	3 (16.67)3
ADLT	20	10 (50.00)	10 (50.00)1,2	11 (55.00)	9 (45.00)3,4
ADHT	20	12 (60.00)	8 (40.00)1,2	9 (45.00)	11 (55.00)3,4

^1,3Represents that the expressions of Ki-67 and Caspase-3 in the BC group were statistically different when compared to that in the AD group or the ADLT group or the ADHT group (P < 0.05, respectively) and (P < 0.05, respectively); ^2,4Represents that the expressions of Ki-67 and Caspase-3 in the AD group were statistically different with those in the ADLT group and the ADHT group (P < 0.05, respectively) and (P < 0.05, respectively).