Copyright
©The Author(s) 2017.
World J Gastroenterol. Oct 21, 2017; 23(39): 7191-7197
Published online Oct 21, 2017. doi: 10.3748/wjg.v23.i39.7191
Published online Oct 21, 2017. doi: 10.3748/wjg.v23.i39.7191
Characteristics (reference ranges) | Patient 1 | Patient 2 | Patient 3 | Patient 4 | Brother | Half-sister |
Sex, age | F, 56 | F, 54 | F, 44 | F, 38 | M, 52 | F, 48 |
Symptom | Fatigue, pruritus | (-) | Fatigue, nausea | (-) | (-) | (-) |
Underlying disease | (-) | Thyroid cancer | (-) | (-) | (-) | (-) |
AST, IU/L (9-39) | 127 | 29 | 311 | 63 | 16 | 17 |
ALT, IU/L (6-45) | 160 | 24 | 509 | 90 | 11 | 13 |
Total/direct bilirubin, mg/dL (0.4-1.3/0.1-0.4) | 1.0 / 0.3 | 0.8 /0.2 | 1.3 / 0.7 | 0.6 / 0.2 | 0.5 / 0.2 | 0.9 / 0.3 |
ALP, IU/L (35-104) | 132 | 122 | 122 | 101 | 83 | 58 |
GGT, IU/L (8-35) | 169 | 63 | 188 | 112 | 14 | 15 |
HBs antigen/antibody | (-/+) | (-/+) | (-/-) | (-/+) | (-/+) | Not done |
Anti-HCV antibody | (-) | (-) | (-) | (-) | (-) | Not done |
Anti-mitochondrial antibody, titer | (+, > 1:1280) | (+, 1:640) | (+, > 1:1280) | (+, 1:640) | (-) | (-) |
Anti-smooth muscle antibody | (-) | (-) | (-) | (-) | (-) | (-) |
Anti-liver-kidney microsome antibody | (-) | (-) | (-) | (-) | Not done | Not done |
Antinuclear antibody | (-) | (-) | (-) | (-) | (-) | (-) |
IgG, mg/dL (700-1600) | 1630 | 1150 | 1790 | 2070 | 1130 | 1210 |
IgA, mg/dL (70-400) | 316 | 226 | 362 | 268 | 287 | 177 |
IgM, mg/dL (40-230) | 421 | 289 | 542 | 542 | 247 | 94.4 |
- Citation: Shin S, Moh IH, Woo YS, Jung SW, Kim JB, Park JW, Suk KT, Kim HS, Hong M, Park SH, Lee MS. Evidence from a familial case suggests maternal inheritance of primary biliary cholangitis. World J Gastroenterol 2017; 23(39): 7191-7197
- URL: https://www.wjgnet.com/1007-9327/full/v23/i39/7191.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i39.7191