Dietrich CF, Dong Y, Jenssen C, Ciaravino V, Hocke M, Wang WP, Burmester E, Moeller K, Atkinson NS, Capelli P, D’Onofrio M. Serous pancreatic neoplasia, data and review. World J Gastroenterol 2017; 23(30): 5567-5578 [PMID: 28852316 DOI: 10.3748/wjg.v23.i30.5567]
Corresponding Author of This Article
Christoph F Dietrich, MD, PhD, MBA, Professor of Medicine, Chief, Medizinische Klinik 2, Caritas-Krankenhaus Bad Mergentheim, Uhlandstr 7, 97980 Bad Mergentheim, Germany. christoph.dietrich@ckbm.de
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Aug 14, 2017; 23(30): 5567-5578 Published online Aug 14, 2017. doi: 10.3748/wjg.v23.i30.5567
Table 1 Baseline characteristics of serous pancreatic neoplasia patients
Characteristic
SPN patients (n = 287)
Age (yr)
mean ± SD
57.3 ± 14.2
Range
18-85
Female/Male
229/58
Symptoms
Pancreatitis
5
Weight loss
9
Anemia
1
Incidental finding
272
Histological results
Surgery
249
EUS FNA (22G)
31
TUS-Bx (18 G)
7
Table 2 Conventional B mode ultrasound findings of serous pancreatic neoplasia n (%)
Characteristic
SPN lesions (n = 287)
Location
Head/neck
113 (39.3)
Body
89 (31.0)
Tail
85 (29.6)
Size of lesions (mm)
mean ± SD
38.7 ± 26.2
Range
4-160
Number of lesions
Single
281 (97.9)
Multiple
6 (2.1)
B mode aspect
Microcystic mix
31 (10.8)
Macrocystic
96 (33.4)
Solid and cystic
133 (46.3)
Solid
27 (9.4)
B mode echogenicity
Anechoic
10 (3.4)
Hypoechoic
271 (94.4)
Hyperechoic
6 (2.2)
CDI vessel detectable
Avascular
228 (79.4)
Macrovessels detectable
59 (20.6)
CDI vascular pattern (n = 59 with macrovessels)
Central artery
26 (44.1)
Typical spoke wheel appearance
21 (35.6)
No specifics
12 (20.3)
Table 3 Contrast enhanced ultrasound imaging features of serous pancreatic neoplasia lesions n (%)
Characteristic
SPN lesions (n = 173)
Arterial phase
Hyperenhancement
63 (36.5)
Isoenhancement
107 (61.8)
Hypoenhancement
3 (1.7)
Late phase
Hyperenhancement
39 (22.5)
Isoenhancement
129 (74.6)
Hypoenhancement
5 (2.9)
Table 4 Endoscopic ultrasound and contrast enhanced endoscopic ultrasound imaging features of serous pancreatic neoplasia lesions n (%)
Characteristic
SPN lesions (n = 61)
EUS
Anechoic
2 (3.3)
Hypoechoic
56 (91.8)
Isoechoic
3 (4.9)
EUS-CDI vessel detectable
Avascular
0
Macrovessels detectable
61 (100)
EUS-CDI vascular pattern (n = 61)
Central artery
26 (42.6)
Typical spoke wheel appearance
15 (24.6)
No specifics
20 (32.8)
CE-EUS (n = 54)
Hyperenhancement
54 (100)
Isoenhancement
0
Hypoenhancement
0
Final EUS-Diagnosis
“Eyecatcher”
49 (80.3)
Typical SCA
5 (8.2)
Unclear macrocyst
6 (9.8)
Citation: Dietrich CF, Dong Y, Jenssen C, Ciaravino V, Hocke M, Wang WP, Burmester E, Moeller K, Atkinson NS, Capelli P, D’Onofrio M. Serous pancreatic neoplasia, data and review. World J Gastroenterol 2017; 23(30): 5567-5578