Serous pancreatic neoplasia, data and review

Table 1 Baseline characteristics of serous pancreatic neoplasia patients

Characteristic	SPN patients (n = 287)
Age (yr)
mean ± SD	57.3 ± 14.2
Range	18-85
Female/Male	229/58
Symptoms
Pancreatitis	5
Weight loss	9
Anemia	1
Incidental finding	272
Histological results
Surgery	249
EUS FNA (22G)	31
TUS-Bx (18 G)	7

SPN: Serous pancreatic neoplasia; EUS: Endoscopic ultrasound; FNA: Fine needle aspiration; TUS-Bx: Transabdominal biopsy.

Table 2 Conventional B mode ultrasound findings of serous pancreatic neoplasia n (%)

Characteristic	SPN lesions (n = 287)
Location
Head/neck	113 (39.3)
Body	89 (31.0)
Tail	85 (29.6)
Size of lesions (mm)
mean ± SD	38.7 ± 26.2
Range	4-160
Number of lesions
Single	281 (97.9)
Multiple	6 (2.1)
B mode aspect
Microcystic mix	31 (10.8)
Macrocystic	96 (33.4)
Solid and cystic	133 (46.3)
Solid	27 (9.4)
B mode echogenicity
Anechoic	10 (3.4)
Hypoechoic	271 (94.4)
Hyperechoic	6 (2.2)
CDI vessel detectable
Avascular	228 (79.4)
Macrovessels detectable	59 (20.6)
CDI vascular pattern (n = 59 with macrovessels)
Central artery	26 (44.1)
Typical spoke wheel appearance	21 (35.6)
No specifics	12 (20.3)

SPN: Serous pancreatic neoplasia; CDI: Color Doppler imaging.

Table 3 Contrast enhanced ultrasound imaging features of serous pancreatic neoplasia lesions n (%)

Characteristic	SPN lesions (n = 173)
Arterial phase
Hyperenhancement	63 (36.5)
Isoenhancement	107 (61.8)
Hypoenhancement	3 (1.7)
Late phase
Hyperenhancement	39 (22.5)
Isoenhancement	129 (74.6)
Hypoenhancement	5 (2.9)

CEUS: Contrast enhanced ultrasound; SPN: Serous pancreatic neoplasia.

Table 4 Endoscopic ultrasound and contrast enhanced endoscopic ultrasound imaging features of serous pancreatic neoplasia lesions n (%)

Characteristic	SPN lesions (n = 61)
EUS
Anechoic	2 (3.3)
Hypoechoic	56 (91.8)
Isoechoic	3 (4.9)
EUS-CDI vessel detectable
Avascular	0
Macrovessels detectable	61 (100)
EUS-CDI vascular pattern (n = 61)
Central artery	26 (42.6)
Typical spoke wheel appearance	15 (24.6)
No specifics	20 (32.8)
CE-EUS (n = 54)
Hyperenhancement	54 (100)
Isoenhancement	0
Hypoenhancement	0
Final EUS-Diagnosis
“Eyecatcher”	49 (80.3)
Typical SCA	5 (8.2)
Unclear macrocyst	6 (9.8)

EUS: Endoscopic ultrasound; EUS-CDI: Endoscopic ultrasound color Doppler Imaging; CE-EUS: Contrast enhanced endoscopic ultrasound; SPN: Serous pancreatic neoplasia; SCA: Serous cystadenoma.