Second-look surgery plus hyperthermic intraperitoneal chemotherapy for patients with colorectal cancer at high risk of peritoneal carcinomatosis: Does it really save lives?

Table 1 Risk of recurrence in function of clinical and histopathological characteristics of tumors

	Estimated incidence of peritoneal metastases observed in follow-up
Clinical characteristic
Peritoneal nodules detected during primary cancer resection	70%
Ovarian metastases	60%
Perforation through the primary cancer	50%
Adjacent organ or structure invasion	20%
Signet-ring histology	20%
Fistula formation	20%
Obstruction of primary cancer	20%
Histopathological characteristic
Positive resection margin	80%
Positive cytology before or after resection	40%
Positive imprint cytology	40%
Positive lymph nodes at or near resection margin	20%
T3/T4 mucinous cancer	40%