Zhang JL, Liu M, Yang Q, Lin SY, Shan HB, Wang HY, Xu GL. Effects of omeprazole in improving concurrent chemoradiotherapy efficacy in rectal cancer. World J Gastroenterol 2017; 23(14): 2575-2584 [PMID: 28465642 DOI: 10.3748/wjg.v23.i14.2575]
Corresponding Author of This Article
Guo-Liang Xu, Professor, Department of Endoscopy and Laser, Sun Yat-Sen University Cancer Center, 651 Dongfeng East Road, East Building, Guangzhou 510060, Guangdong Province, China. xugl@sysucc.org.cn
Research Domain of This Article
Oncology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
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Table 5 Univariate Cox analysis of the impact of various characteristics on patient survival
Characteristics
DFS
P value
OS
P value
HR
95%CI
HR
95%CI
Sex
Male vs Female
0.91
0.42-1.65
0.800
0.93
0.41-2.09
0.860
Age (yr)
< 60 vs ≥ 60
0.80
0.40-1.62
0.530
1.05
0.50-2.19
0.910
BMI
< 25 vs ≥ 25
0.22
0.05-0.93
0.039
0.26
0.06-1.11
0.069
Tumor size (cm)
≤ 3 vs > 3
1.23
0.60-2.51
0.570
0.98
0.46-2.08
0.960
Tumor grade
1 vs 2, 3
1.08
0.47-2.50
0.850
0.96
0.41-2.26
0.930
cTNM
II vs III
2.23
0.92-5.41
0.075
1.96
0.80-4.80
0.144
CEA (ng/mL)
< 5 vs ≥ 5
0.91
0.46-1.81
0.790
0.72
0.34-1.51
0.390
CA199 (U/mL)
< 35 vs ≥ 35
1.77
0.77-4.08
0.180
1.30
0.50-3.40
0.600
CRT efficacy
Poor vs good
0.43
0.19-0.95
0.036
0.55
0.24-1.24
0.150
ypTNM
ypcr, I,II vs III
1.61
1.14-2.27
0.006
1.46
1.01-2.11
0.045
Adjuvant CT
Non vs yes
0.69
0.30-1.60
0.390
0.60
0.25-1.40
0.240
EOU
Non vs yes
1.17
0.59-2.31
0.660
1.13
0.54-2.37
0.750
EOG
Non vs yes
0.30
0.90-0.97
0.044
0.37
0.11-1.23
0.110
Citation: Zhang JL, Liu M, Yang Q, Lin SY, Shan HB, Wang HY, Xu GL. Effects of omeprazole in improving concurrent chemoradiotherapy efficacy in rectal cancer. World J Gastroenterol 2017; 23(14): 2575-2584