Zhang L, Tu L, Chen J, Song J, Bai T, Xiang XL, Wang RY, Hou XH. Health-related quality of life in gastroesophageal reflux patients with noncardiac chest pain: Emphasis on the role of psychological distress. World J Gastroenterol 2017; 23(1): 127-134 [PMID: 28104988 DOI: 10.3748/wjg.v23.i1.127]
Corresponding Author of This Article
Xiao-Hua Hou, MD, PhD, Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Road, Wuhan 430022, Hubei Province, China. houxh@medmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Observational Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Table 2 Gastroesophageal reflux disease scores and chest pain severity and frequency in gastroesophageal reflux disease patients with or without chest pain
GERD without CP (n = 182)
GERD with NCCP (n = 124)
GERD with CCP (n = 52)
P value
GERD score (mean ± SD)
15.26 ± 3.79
15.73 ± 3.54
15.00 ± 3.44
0.428
Chest pain severity, n (%)
-
120
52
0.038
Mild
37 (30.8)
6 (11.5)
Moderate
39 (32.5)
19 (36.5)
Severe
37 (30.8)
22 (42.4)
Incapacitating
7 (5.9)
5 (9.6)
Chest pain frequency, n (%)
-
120
52
0.046
< once per month
43 (35.8)
14 (26.9)
≥ once per month
49 (40.8)
16 (30.8)
≥ once per week
28 (23.4)
22 (42.3)
Table 3 Anxiety and depression in gastroesophageal reflux disease patients with or without chest pain
Table 5 Influence of physical and psychological symptoms on quality of life in gastroesophageal reflux disease patients with chest pain: A multivariate analysis
Citation: Zhang L, Tu L, Chen J, Song J, Bai T, Xiang XL, Wang RY, Hou XH. Health-related quality of life in gastroesophageal reflux patients with noncardiac chest pain: Emphasis on the role of psychological distress. World J Gastroenterol 2017; 23(1): 127-134