Hepatitis E virus: An ancient hidden enemy in Latin America

Table 1 Hepatitis E virus genotypes reported for Latin America

Genotype	Region	Species1			Detection method/input specimen2
		Humans	Swine	Other3	RT-PCR	Serum
Genotype 1	Uruguay	X			X	X
	Venezuela	X			X
	Cuba	X				X
	Mexico	X			X	X
Genotype 2	Mexico	X	X		X	X
Genotype 3	Argentina	X	X	X	X	X
	Brazil	X	X	X	X	X
	Bolivia	X				X
	Cuba	X			X
	Venezuela	X			X
	México		X	X	X
	Uruguay	X			X
	Chile	X			X	X
	Costa Rica		X		X
Genotype 4	China, Japan, Taiwan	X	X		X	X
	(not in Latin America)

¹According to reports found in PubMed, indicates infection regardless of disease condition of the host (with or without clinical signs).

²Origin of the host in analyzed samples. Reverse Transcription PCR (RT-PCR) was the method used to detect genomic RNA of HEV. When serum was the input material, the detection of anti-HEV specific antibodies (seroconversion) was indicative of current contact (active infection) or past infection.

³Host or developed in chickens, deer, rodent and other mammals.