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©The Author(s) 2016.
World J Gastroenterol. Dec 7, 2016; 22(45): 10038-10044
Published online Dec 7, 2016. doi: 10.3748/wjg.v22.i45.10038
Published online Dec 7, 2016. doi: 10.3748/wjg.v22.i45.10038
Table 1 General information on patients with serrated lesions in upper gastrointestinal tract
| n (%) | |
| Total | 21 |
| Mean age (yr), mean ± SD | 55.3 ± 17.2 |
| Gender, male | 11 (52.4) |
| Body mass index (kg/m2), mean ± SD | 24.9 ± 5.8 |
| 18.5-23.9 | 13 (61.9) |
| ≥ 24.0 | 8 (38.1) |
| History of smoking | 7 (33.3) |
| Alcohol consumption | 10 (47.6) |
| Family history of gastric cancer | 1 (4.8) |
| Indications for endoscopy | |
| Upper abdominal pain | 5 (23.8) |
| Nausea, vomit and reflux | 4 (19.0) |
| Anemia and edema | 4 (19.0) |
| Positive fecal occult blood test | 3 (14.3) |
| A history of gastric polyps | 3 (14.3) |
| Dyspepsia | 2 (9.5) |
Table 2 Clinical features of serrated lesions in upper gastrointestinal tract
| n (%) | |
| Size (mm), mean ± SD | 11.7 ± 10.3 |
| ≤ 5 | 8 (38.1) |
| 5-10 | 4 (19.0) |
| 10-20 | 6 (28.6) |
| 20-30 | 1 (4.8) |
| ≥ 30 | 2 (9.5) |
| Distribution | |
| Esophagus | 1 (4.8) |
| Cardia | 3 (14.3) |
| Corpus | 9 (42.9) |
| Antrum | 5 (23.8) |
| Duodenum | 3 (14.3) |
| Morphology | |
| Serrated hyperplasia | 6 (28.6) |
| Hyperplastic polyps | 8 (38.1) |
| Adenoma | 6 (28.6) |
| Adenocarcinoma | 1 (4.8) |
| Situation of serrated lesions in mucosal lesions | |
| Inflammation or ulcer | 3 (14.3) |
| Serrated polyps | 14 (66.7) |
| Ménétrier gastropathy | 3 (14.3) |
| Duodenal cancer | 1 (4.8) |
| Colonoscopy findings | 18 |
| No-polyp | 4 (22.2) |
| Hyperplastic polyps | 7 (38.9) |
| Non-advanced adenomas | 3 (16.7) |
| Advanced adenomas | 4 (22.2) |
| Tubular adenoma with high grade dysplasia | 1 (5.6) |
| Tubulovillous adenoma | 2 (11.1) |
| Adenoma > 10 mm | 1 (5.6) |
Table 3 Colonoscopy findings in the patients with serrated lesions in upper gastrointestinal tract
| Serrated lesions in upper gastrointestinal tract mucosal lesions (n) | Colonoscopy findings (n) |
| Inflammation or ulcer (3) | HPs (1) |
| HPs (8) | AA (2), NAA (1), HPs (2) |
| Serrated adenoma (6) | AA (2), NAA (2), HPs (2) |
| Ménétrier gastropathy (3) | HPs (2) |
| Duodenal cancer (1) | Absent |
Table 4 Prevalence of colorectal adenoma in patients with serrated lesions in upper gastrointestinal tract and the control group n (%)
| Patients with serrated lesions in UPGI(n = 18) | Average group(n = 72) | OR (95%CI) | P value | |
| Colorectal adenoma | 7 (38.9) | 8 (11.1) | 5.091 (1.534-16.890) | 0.010 |
| Non-advanced adenoma | 3 (16.7) | 5 (6.9) | 2.680 (0.576-12.463) | 0.195 |
| Advanced adenoma | 4 (22.2) | 3 (4.2) | 6.571 (1.322-32.660) | 0.028 |
- Citation: Cao HL, Dong WX, Xu MQ, Zhang YJ, Wang SN, Piao MY, Cao XC, Wang BM. Clinical features of upper gastrointestinal serrated lesions: An endoscopy database analysis of 98746 patients. World J Gastroenterol 2016; 22(45): 10038-10044
- URL: https://www.wjgnet.com/1007-9327/full/v22/i45/10038.htm
- DOI: https://dx.doi.org/10.3748/wjg.v22.i45.10038