Regional but fatal: Intraperitoneal metastasis in gastric cancer

Table 1 Twenty-four up-regulated and 17 down-regulated genes in gastric cancer cells from malignant ascites compared with those from primary lesions

Gene expression level	Gene name	Gene function
Down-regulated
	Nucleobinding 2	Signaling (apoptosis)
	Acyl-Coenzyme A dehydrogenase	Signaling
	Chaperonin containing TCP1	Signaling
	FKBP54	Signaling
	Histone deacetylase 3	Signaling
	p27kip	Signaling
	PAK-interacting exchange factor alpha	Signaling
	CD4	Immune response
	IL4 stat	Immune response
	L2 receptor gamma	Immune response
	IGFBP2	Growth and metabolism
	RAD51 homologue C	Chromosome stability
	Heterogenous nuclear ribonucleoprotein	Cell adhesion
	Integrin β4	Cell adhesion
	Tubulin beta-1 chain	Cell adhesion
	Death associated protein	Apoptosis
	H2A histone family member L	Apoptosis
Up-regulated
	Dopa decarboxylase	Signaling or progression
	Caveolin-3	Signaling (modification)
	CD9	Signaling
	Dystroglycan1	Signaling
	Inositol triphosphate receptor	Signaling
	LMO 7	Signaling
	Sodium/hydrogen exchanger, isoform 1	Signaling
	Cystein protease (legumain)	Invasion
	Myosin 6	Intracellular organelle transport
	Destrin (actin depolymerising factor)	Interaction with extracellular matrix
	Renal tumor antigen RAGE1	Immune response
	Aldehyde dehydrogenase	Drug metabolism
	Aldo-keto reductase family 1	Drug metabolism
	Keratin 14	Cell adhesion, invasion
	Keratin 7	Cell adhesion, invasion
	Keratin 8	Cell adhesion, invasion
	CD44	Cell adhesion
	Desmoplakin (DPI, DPII)	Cell adhesion
	Galectin 3 (lectin)	Cell adhesion
	Integrin alpha3	Cell adhesion
	Occludin	Cell adhesion
	S100 A10 (ligand of Annexin II)	Cell adhesion
	Leukocyte elastase inhibitor	Apoptosis
	TGFb-induced anti-apoptotic factor	Apoptosis