Weight loss endoscopy: Development, applications, and current status

Table 1 Current status of selected endoscopic bariatric therapies

Device	Procedure	Mechanism	Regulatory status
Orbera	Intragastric balloon	Space-occupying device	FDA-approved
Integrated dual balloon	Intragastric balloon	Space-occupying device	FDA-approved
OverStitch	Endoscopic sleeve gastroplasty	Gastric remodeling	FDA-approved1
Incisionless operating platform	Primary obesity surgery endolumenal	Gastric remodeling	Under FDA review
Articulating circular endoscopic stapler	Gastroplasty	Gastric remodeling	In human trials
AspireAssist	Aspiration therapy	Aspiration	FDA-approved
Self-assembling magnets	Endoscopic enteral anastomosis	Dual-path enteral bypass	In human trials
OverStitch	Transoral outlet reduction for revision of gastric bypass	Anastomotic reduction	FDA-approved1
Incisionless operating platform	Revision obesity surgery endolumenal for revision of gastric bypass	Anastomotic and pouch reduction	FDA-approved1

¹Device is FDA-approved for tissue apposition. FDA: Food and Drug Administration.