Emerging roles of non-coding RNAs in gastric cancer: Pathogenesis and clinical implications

Table 1 Dysregulation of lncRNAs in gastric cancer

lncRNAs	Expression	Biological processes	Targets	Ref.
ABDH11-AS1	Up	Unknown	Unknown	[41]
AC138128.1	Up	Unknown	Unknown	[42]
AK058003	Up	Promote migration and invasion	γ-Synuclein	[3]
ANRIL	Up	Promote proliferation and tumorigenesis	miR-99a/miR-449a	[44]
CARLo-5	Up	Promote proliferation	Unknown	[45]
CCAT1	Up	Promote proliferation and migration	Unknown	[46,47]
CCAT2	Up	Unknown	Unknown	[48]
GACAT3	Up	Unknown	Unknown	[49,50]
GAPLINC	Up	Promote proliferation, invasion and tumorigenesis	CD44	[51]
GHET1	Up	Promote proliferation and tumorigenesis	c-myc	[52]
H19	Up	Promote proliferation and suppress apoptosis; enhance metastasis	p53, miR-675/RUX1, CALN1	[53-55]
HIF1A-AS2	Up	Unknown	unknown	[56]
HOTAIR	Up	Promote migration, invasion, EMT and metastasis	Snail, MMP1, MMP3, HER2, SUZ12	[57-62]
HULC	Up	Promote proliferation, invasion and EMT; suppress apoptosis	Unknown	[63]
linc00152	Up	Unknown	Unknown	[64]
linc-UBC1	Up	Promote proliferation and invasion	Unknown	[65]
LSINCT5	Up	Promote proliferation	Unknown	[66]
MALAT1	Up	Promote proliferation	SF2/ASF	[67]
MRUL	Up	Promote MDR	ABCB1	[68]
PVT1	Up	Promote cell proliferation	p15, p16	[69]
SPRY4-IT1	Up	Promote tumorigenesis	Unknown	[70]
TINCR	Up	Regulate cell proliferation and apoptosis	KLF2	[71]
UCA1	Up	Unknown	Unknown	[72]
LEIGC	Down	Inhibit migration and EMT	Unknown	[73]
FENDRR	Down	Suppress migration, invasion and metastasis	FN1	[74]
AA174084	Down	Unknown	Unknown	[75]
BM742401	Down	Suppress migration, invasion and metastasis	Unknown	[76]
FER1L4	Down	Unknown	miR-106a-5p	[77,78]
GACAT1	Down	Unknown	Unknown	[79,80]
GACAT2	Down	Unknown	Unknown	[50,81]
GAS5	Down	Inhibit proliferation and tumorigenesis	E2F1, p21	[82]
LET	Down	Unknown	Unknown	[83]
MEG3	Down	Inhibit proliferation and promote apoptosis	p53	[54,85]
ncRuPAR	Down	Unknown	PAR1	[86]