Serum vitamin D and colonic vitamin D receptor in inflammatory bowel disease

Table 1 Demographic information for control and inflammatory bowel disease patients

	Control (n = 10)	IBD (n = 10)
Sex
Male	4	6
Female	6	4
Mean age (yr)	56.70 ± 1.64	40.40 ± 5.27a
IBD diagnosis
CD		7
UC		3

^aP < 0.05. CD: Crohn’s disease; IBD: Inflammatory bowel disease; UC: Ulcerative colitis.

Table 2 Demographic and disease information for control and inflammatory bowel disease patients

Patient ID	Age (yr)	Sex	Diagnosis	IBD duration (yr)	Medications	Colonoscopy findings
UC1	63	F	Ulcerative colitis	15	Mesalamine, Azathioprine	Proctosigmoiditis
CD1	29	F	Crohn’s disease	2	Adalimumab	Active mild colitis
CD2	41	M	Crohn’s disease1	16	Enalapril	Active Crohn’s disease at ileocolonic anastomosis
UC2	25	M	Ulcerative colitis	2	Sulfazalazine	Mild proctosigmoiditis
CD3	23	M	Crohn’s disease	3	Adalimumab, Azathioprine, folic acid	Active Crohn’s disease with ileocecal valve involvement
CD4	55	M	Crohn’s disease1	10	Mesalamine	Crohn’s ileocolitis with small external hemorrhoids
CD5	38	M	Crohn’s disease1	8	Infliximab	Active disease at ileocolonic anastomosis
CD6	32	F	Crohn’s disease1	8	Infliximab	Mild sigmoiditis with internal/external hemorrhoids
CD7	28	M	Crohn’s disease1	2	Adalimumab	Friable ileocecal valve anastomosis with small aphtous ulcer; mild distal proctitis
UC3	70	F	Ulcerative colitis	8	Mesalamine	Mild proctitis
C1	50	F	HTN, dyslipidemia, DM-2	-	Irbesartan, Simvastatine, Glipizide, Insulin, Clonazepam	Normal study
C2	55	F	HTN	-	Losartan	Single diminutive sessile polyp
C3	67	M	DM-2, post-liver transplant secondary to ETOH	-	Folic acid, Glipizide, Tacrolimus	Hemorrhoids internal/external
C4	54	M	HIV	-	Efavirnez, Tenofovir, Lamivudine	External hemorrhoids
C5	63	M	HTN, hypothyroidism, CKD, post-liver transplant secondary to ETOH	-	Tacrolimus, Propranolol, Pepcid, Simvastatin	Normal study
C6	57	F	Hypothyroidism, GERD	-	Ranitidine, Omeprazole, Levothyroxine
C7	55	M	HTN, dyslipidemia, anxiety, depression	-	Losartan, Clopidrogel, Amlodipine, Simvastatin, Clonazepam, Trazodone, Venlafaxine	Two polyps < 1 cm, both tubular adenomas
C8	59	F	Hypothyroidism, depression, anxiety	-	Levothyroxine, Gabapentin, Sertraline, Clonazepam, Estazolam	Moderate pandiverticulosis
C9	56	F	DM-2, dyslipidemia, NASH	-	Simvastatin, Aspirin, Gliburide	Normal sigmoidoscopy/normal virtual colonoscopy
C10	51	F	None reported	-	none	Two small sessile polyps-hyperplastic polyps; left side diverticulosis

¹IBD-related surgery. F: Female; M: Male; HTN: Hypertension; DM-2: Type 2 diabetes mellitus; HIV: Human immunodeficiency virus; CKD: Chronic kidney disease; GERD: Gastroesophageal reflux disease; NASH: Nonalcoholic steatohepatitis; IBD: Inflammatory bowel disease.