Proteoglycans in liver cancer

doi:10.3748/wjg.v22.i1.379

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 7, 2016; 22(1): 379-393
Published online Jan 7, 2016. doi: 10.3748/wjg.v22.i1.379

Table 1 Classification of proteoglycans

Localization	Eponym	Gene symbol	GAG
Intracellular	Serglycin	SRGN	Hep
Membrane
SLIPs
	Syndecan-1	SDC1	HS/CS
	Syndecan 2-4	SDC2-4	HS
GRIPs
	Glypican 1-6	GPC 1-6	HS/CS
Other
	Betaglycan	TGFBR3	HS/CS
	CD44	CD44	CS
Extracellular
SLRPs
Class I
	Decorin	DCN	DS/CS
	Biglycan	BGN	CS
	Asporin	ASPN	-
Class II
	Fibromodulin	FMOD	KS
	Lumican	LUM	KS
	Keratocan	KERA	KS
	PRELP	PRELP	-
	Osteoadherin	OMD	KS
Class III
	Epiphycan	EPYC	CS/DS
	Osteoglycin	OGN	-
Pericellular
BM zone
	Agrin	AGRN	HS
	Collagen XVIII	COL18A1	HS
	Aggrecan	ACAN	CS/KS
Hyalectans
	Versican	VCAN	CS
	Neurocan	NCAN	CS
	Brevican	BCAN	CS

SLIPs: Syndecan-like integral membrane proteoglycans; GRIPs: Glypican-related integral membrane heparan sulfate proteoglycans; SLRPs: Small leucine-rich proteoglycans; BM: Basement membrane.

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Citation: Baghy K, Tátrai P, Regős E, Kovalszky I. Proteoglycans in liver cancer. World J Gastroenterol 2016; 22(1): 379-393
URL: https://www.wjgnet.com/1007-9327/full/v22/i1/379.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i1.379