Copyright
©The Author(s) 2015.
World J Gastroenterol. Oct 21, 2015; 21(39): 11168-11178
Published online Oct 21, 2015. doi: 10.3748/wjg.v21.i39.11168
Published online Oct 21, 2015. doi: 10.3748/wjg.v21.i39.11168
Table 1 Patient characteristics
| No. | Sex | Age (yr) | Location | Size (mm) | Metastases | UICC stage | Vaccine (times) | OS (d) | PFS (d) | HLA type | Best overall tumor response | |||||
| HLA-A | DRB1 | DPB1 | ||||||||||||||
| 1 | M | 70 | Body | 22 | Peritonitis | IV | 35 | 582 | 440 | 02:01 | 24:02 | 04:05 | 15:02 | 05:01 | 09:01 | Stable disease |
| 2 | M | 68 | Body | 15 | Liver, lymph nodes | IV | 46 | 717 | 208 | 24:02 | 33:03 | 08:03 | 13:02 | 02:02 | 04:01 | Stable disease |
| 3 | F | 49 | Head | 18 | Liver, peritonitis, lymph nodes | IV | 7 | 133 | 26 | 02:01 | 24:02 | 04:05 | 09:01 | 02:02 | 05:01 | Progressive disease |
| 4 | M | 35 | Body | 25 | Liver, lymph nodes | IV | 6 | 283 | 147 | 02:01 | - | 09:01 | 15:01 | 02:01 | 05:01 | Stable disease |
| 5 | F | 72 | Body | 22 | Peritonitis, lymph nodes | IV | 14 | 215 | 109 | 02:06 | 24:02 | 08:02 | 12:01 | 02:01 | 05:01 | Stable disease |
| 6 | F | 69 | Body-tail | 45 | Lymph nodes | IV | 71+ | 1050+ | 545 | 24:02 | 33:03 | 13:02 | 15:01 | 04:01 | 13:01 | Stable disease |
| 7 | M | 39 | Head-body | 30 | Peritonitis | IV | 20 | 325 | 290 | 02:10 | 24:02 | 15:01 | 15:02 | 02:02 | 09:01 | Stable disease |
Table 2 Wilms’ tumor 1-specific delayed-type hypersensitivity reactions
| Patient | Gemcitabine | HLA-A*02:01 | HLA-A*24:02 | HLA-DRB1/DPB1 | |||||||||||||||||||||||||||||||
| No. | Vaccine times | Vaccine times | Vaccine times | ||||||||||||||||||||||||||||||||
| Pre | Post | 1 | 5 | 10 | 15 | 20 | 25 | 30 | 35 | 40 | 45 | 70 | 1 | 5 | 10 | 15 | 20 | 25 | 30 | 35 | 40 | 45 | 70 | 1 | 5 | 10 | 15 | 20 | 25 | 30 | 35 | 40 | 45 | 70 | |
| 1 | - | - | + | + | ++ | ++ | ++ | ++ | + | - | ND | + | + | ++ | ++ | ++ | ++ | + | - | ND | + | + | ++ | ++ | ++ | ++ | + | - | ND | ||||||
| 2 | - | - | - | - | - | - | - | - | - | - | - | - | ND | + | + | ++ | ++ | + | + | + | + | + | - | ND | + | + | ++ | ++ | + | + | + | + | + | - | ND |
| 3 | - | - | - | - | ND | - | - | ND | - | - | ND | ||||||||||||||||||||||||
| 4 | - | - | - | - | ND | - | - | ND | - | - | ND | ||||||||||||||||||||||||
| 5 | - | - | - | - | - | ND | - | - | - | ND | - | - | - | ND | |||||||||||||||||||||
| 6 | - | - | - | - | - | - | - | - | - | - | - | - | - | + | + | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ | + | + | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ |
| 7 | - | - | - | - | - | - | - | ND | - | - | + | + | - | ND | - | + | + | - | ND | ||||||||||||||||
- Citation: Tsukinaga S, Kajihara M, Takakura K, Ito Z, Kanai T, Saito K, Takami S, Kobayashi H, Matsumoto Y, Odahara S, Uchiyama K, Arakawa H, Okamoto M, Sugiyama H, Sumiyama K, Ohkusa T, Koido S. Prognostic significance of plasma interleukin-6/-8 in pancreatic cancer patients receiving chemoimmunotherapy. World J Gastroenterol 2015; 21(39): 11168-11178
- URL: https://www.wjgnet.com/1007-9327/full/v21/i39/11168.htm
- DOI: https://dx.doi.org/10.3748/wjg.v21.i39.11168