MicroRNA expression in hepatitis C virus-related malignancies: A brief review

Table 1 MicroRNAs with an attributed biological significance in hepatitis C virus-related hepatocellular carcinoma development and behavior

Name		Ref.
miR-192/-215	Enhancing HCV replication	[16]
miR-193b	Altered sensitivity to chemotherapy, inhibition of apoptosis	[19]
miR-198	Cell proliferation and migration	[14,15]
miR-320	Cell proliferation	[16]
miR-491	Cell proliferation, inhibition of apoptosis	[16]
miR-24	Liver fibrosis	[17]
miR-122	Modulation of HCV RNA expression	[14]
miR-199a	Poor survival, shorter time to disease recurrence, cell proliferation	[23]

Table 2 Highly dysregulated microRNAs identified in studies regarding hepatitis C virus-related hepatocellular carcinoma

Name		In vitro/patient-derived samples	Ref.
miR-24	Down	In vitro	[17]
mi-122	Up	Patient derived samples	[14]
miR-149	Up	In vitro	[17]
miR-181a	Down	In vitro	[17]
miR-192/-215	Up	In vitro	[16]
miR-193b	Up	In vitro	[19]
miR-194	Up	In vitro	[16]
miR-198	Down	In vitro	[14,15]
miR-198	Down	Patient derived samples	[14]
miR-199a	Down	Patients derived samples	[23]
miR-210	Down	In vitro	[17]
miR-221	Down	In vitro	[17]
miR-320	Down	In vitro	[16]
miR-373*	Up	In vitro	[17]
miR-455-3p	Down	In vitro	[17]
miR-491	Down	In vitro	[16]
miR-638	Up	In vitro	[17]
miR-664	Down	In vitro	[17]
miR-887	Up	In vitro	[17]
miR-923	Down	In vitro	[17]
miR-940	Up	In vitro	[17]
miR-1181	Up	In vitro	[17]
miR-1234	Up	In vitro	[17]
miR-1469	Up	In vitro	[17]
Urinary
miR-516-5p	Down	Patient derived samples	[22]
miR-532	Up	Patient derived samples	[22]
miR-618	Up	Patient derived samples	[22]
miR-625	Up	Patient derived samples	[22]
miR-650	Down	Patient derived samples	[22]