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Jul 21, 2015 (publication date) through Oct 31, 2025
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Publication Name
World Journal of Gastroenterology
ISSN
1007-9327
Publisher of This Article
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Control Study
Copyright ©The Author(s) 2015.
World J Gastroenterol. Jul 21, 2015; 21(27): 8358-8365
Published online Jul 21, 2015. doi: 10.3748/wjg.v21.i27.8358
Table 1 Characteristics of the early gastric cancer and advanced gastric cancer groups n (%)
OverallEGC groupAGC groupP value
(n = 413)(n = 184)(n = 229)
Mean age (mean ± SD, yr)61.3 ± 11.662.1 ± 10.260.8 ± 12.60.263
Gender
Male293 (70.9)137 (74.5)156 (68.1)0.159
Female120 (29.1)47 (25.5)73 (31.9)
Smoking229 (55.4)110 (59.8)109 (47.6)0.014
Alcohol190 (46.0)97 (52.7)93 (40.6)0.014
H. pylori infection258 (62.5)105 (57.1)153 (66.8)0.042
Histology
Differentiated262 (63.4)184 (100)78 (34.1)< 0.001
Undifferentiated151 (36.6)0151 (65.9)
Follow-up duration (mean ± SD, months)37.2 ± 15.936.9 ± 14.937.4 ± 16.70.697
EGC: Early gastric cancer; AGC: Advanced gastric cancer; SD: Standard deviation; H. pylori: Helicobacter pylori.
Full Size Table
Table 2 Incidence of second primary cancers in gastric cancer patients n (%)
OverallEGC groupAGC groupP value
(n = 413)(n = 184)(n = 229)
Second primary cancer38 (9.2)17 (9.2)21 (9.2)0.981
Synchronous cancer18 (4.4)8 (4.3)10 (4.4)0.993
Metachronous cancer20 (4.8)9 (4.9)11 (4.8)0.967
EGC: Early gastric cancer; AGC: Advanced gastric cancer.
Full Size Table
Table 3 Distribution of second primary cancers according to gastric cancer group n (%)
LocationOverallEGC groupAGC group
(n = 38)(n = 17)(n = 21)
Lung7 (18.4)3 (17.6)4 (19.0)
Colorectal5 (13.2)2 (11.8)3 (14.3)
Esophagus5 (13.2)2 (11.8)3 (14.3)
Urogenital4 (10.5)2 (11.8)2 (9.5)
Gynecologic3 (7.9)1 (5.9)2 (9.5)
Pancreas3 (7.9)1 (5.9)2 (9.5)
Skin2 (5.3)1 (5.9)1 (4.8)
Hematology2 (5.3)1 (5.9)1 (4.8)
Others7 (18.3)4 (23.4)3 (14.3)
EGC: Early gastric cancer; AGC: Advanced gastric cancer.
Full Size Table
Table 4 Logistic regression analysis of risk factors in the early gastric cancer group
Synchronous cancer
Metachronous cancer
OR (95%CI)P valueOR (95%CI)P value
Age (> 60 yr)0.676 (0.082-5.580)0.5891.151 (0.278-4.768)0.846
Sex (male)0.992 (0.193-5.104)0.9921.488 (0.356-6.214)0.586
Smoking0.392 (0.091-1.696)0.2101.307 (0.316-5.408)0.712
Alcohol0.501 (0.116-2.165)0.3550.418 (0.101-1.726)0.228
H. pylori infection1.294 (0.299-5.594)0.7301.553 (0.376-6.421)0.543
EGC: Early gastric cancer; OR: Odds ratio; CI: Confidence interval; H. pylori: Helicobacter pylori.
Full Size Table
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