Retrospective Study
Copyright ©The Author(s) 2015.
World J Gastroenterol. May 14, 2015; 21(18): 5532-5541
Published online May 14, 2015. doi: 10.3748/wjg.v21.i18.5532
Table 1 Characteristics of the sample
CharacteristicsCaseControl
Children, n296335
Age, yr (mean ± SD)11.89 ± 2.6211.84 ± 2.49
Male sex, %48.649
Ethnicity, %
Caucasian77.582.6
African American5.85.7
Asian6.18.7
Hispanic4.82.4
Native American0.70.3
Table 2 Number of medical clinic visit for each symptom category by mothers and children in case and control families, and correlation between number of mother and child visits
Symptom categoryCase families
Control families
Combined samples
MotherChildrhoMotherChildrhoAll mothersAll childrenrho
mean ± SEmean ± SEmean ± SEmean ± SEmean ± SEmean ± SE
Gastrointestinal3.27 ± 0.18c0.61 ± 0.16a0.0640.20 ± 0.030.20 ± 0.050.0421.62 ± 0.110.39 ± 0.080.219e
Upper respiratory infection2.07 ± 0.14c1.97 ± 0.15c0.290e0.74 ± 0.061.08 ± 0.090.326e1.37 ± 0.081.50 ± 0.090.355e
Asthma0.60 ± 0.13c0.48 ± 0.100.203e0.09 ± 0.020.30 ± 0.080.180e0.32 ± 0.060.37 ± 0.060.204e
Headache1.47 ± 0.42b0.25 ± 0.060.0560.22 ± 0.060.14 ± 0.040.0970.76 ± 0.200.19 ± 0.030.089d
Back pain1.43 ± 0.23c0.17 ± 0.040.168d0.31 ± 0.050.12 ± 0.03-0.0380.77 ± 0.090.14 ± 0.020.080d
All outpatient visits30.25 ± 1.53c12.90 ± 0.80c0.348e10.74 ± 0.438.45 ± 0.490.260e19.80 ± 0.08310.50 ± 0.460.375e
Table 3 Psychological traits in children and their mothers
Psychological traitCase families
Control families
Combined samples
MotherChildrhoMotherChildrhoAll mothersAll childrenrho
mean ± SEmean ± SEmean ± SEmean ± SEmean ± SEmean ± SE
Global psychological distress2.81 ± 0.10a55.16 ± 0.62a0.414b1.22 ± 0.0748.46 ± 0.530.376b1.99 ± 0.0751.65 ± 0.420.484b
Anxiety0.66 ± 0.04a4.64 ± 0.25a0.314b0.30 ± 0.022.65 ± 0.170.354b0.46 ± 0.023.60 ± 0.150.393b
Depression1.01 ± 0.04a2.20 ± 0.15a0.282b0.48 ± 0.031.29 ± 0.090.301b0.77 ± 0.031.72 ± 0.090.345b
Somatization1.15 ± 0.04a3.24 ± 0.16a0.366b0.45 ± 0.021.73 ± 0.100.157b0.78 ± 0.032.43 ± 0.100.374b