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©The Author(s) 2015.
World J Gastroenterol. Mar 21, 2015; 21(11): 3337-3343
Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3337
Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3337
Table 1 Cost assumptions, utility value, transition probabilities in decision analysis of screening for gallstone disease
Parameter | Value |
Annual direct cost (NTD) | |
Screening cost1 | 1382 |
Regular clinics fee2 | 509 |
Laparoscopic cholecystectomy | 11710 |
Hospitalizations and others | 26825 |
Total | 40426 |
Annual indirect cost (NTD) | |
Gross domestic product | 635670 |
Utility (quality of life) value | |
No GSD | 0.92 ± 0.10 |
Single stone | 0.90 ± 0.12 |
Multiple stones | 0.89 ± 0.19 |
Cholecystectomy | 0.88 ± 0.08 |
Annual transition probability (%)[9] | |
No GSD → Single stone | 5.05 |
Single stone → Multiple stones | 10.00 |
Multiple stones → Cholecystectomy | 13.76 |
Table 2 Cost-effectiveness analysis and cost-utility analysis for different screening programs for gallstone disease during 10 years follow-up
Screening strategy | Cost (NTD) | Effectiveness(life-years gained) | Cost/effectiveness (NTD) | ICER (compared to control group) | Utility (QALY) | Cost/utility(NTD) | ICUR (compared to control group) |
Annual | 199856 | 5.1146 | 39076 | Dominate1 | 4.9075 | 40725 | Dominate1 |
Biennial | 215231 | 3.7071 | 58059 | Dominate1 | 3.3180 | 64868 | Dominate1 |
3-yearly | 253908 | 3.5183 | 72168 | Dominate1 | 3.0037 | 84532 | Dominate1 |
4-yearly | 331477 | 3.1724 | 104488 | Dominate1 | 2.9873 | 110962 | Dominate1 |
5-yearly | 368002 | 2.8990 | 126941 | Dominate1 | 2.5906 | 142053 | Dominate1 |
Control group | 508117 | 2.5731 | 197473 | - | 2.5033 | 202979 | - |
Table 3 Sensitivity analysis of cost-effectiveness analysis and cost-utility analysis of different screening programs for Gallstone disease
Variable | Base case | Range | Threshold of CEA | Threshold of CUA |
Annual screening | ||||
Screening cost (NTD) | 1382 | 1000-50000 | 41630 | 40082 |
Indirect cost (NTD) | 231834 | 0-635670 | Dominate1 | Dominate1 |
Percentage of cholecystectomy | 0.8 | 0.1-0.9 | Dominate1 | Dominate1 |
Biennial screening | ||||
Screening cost (NTD) | 1382 | 1000-50000 | 38771 | 37250 |
Indirect cost (NTD) | 231834 | 0-635670 | Dominate1 | Dominate1 |
Percentage of cholecystectomy | 0.8 | 0.1-0.9 | Dominate1 | Dominate1 |
3-yr screening | ||||
Screening cost (NTD) | 1382 | 1000-50000 | 36048 | 36003 |
Indirect cost (NTD) | 231834 | 0-635670 | Dominate1 | Dominate1 |
Percentage of cholecystectomy | 0.8 | 0.1-0.9 | Dominate1 | Dominate1 |
4-yr screening | ||||
Screening cost (NTD) | 1382 | 1000-50000 | 32186 | 31952 |
Indirect cost (NTD) | 231834 | 0-635670 | Dominate1 | Dominate1 |
Percentage of cholecystectomy | 0.8 | 0.1-0.9 | Dominate1 | Dominate1 |
5-yr screening | ||||
Screening cost (NTD) | 1382 | 1000-50000 | 29063 | 28579 |
Indirect cost (NTD) | 231834 | 0-635670 | Dominate1 | Dominate1 |
Percentage of cholecystectomy | 0.8 | 0.1-0.9 | Dominate1 | Dominate1 |
- Citation: Shen HJ, Hsu CT, Tung TH. Economic and medical benefits of ultrasound screenings for gallstone disease. World J Gastroenterol 2015; 21(11): 3337-3343
- URL: https://www.wjgnet.com/1007-9327/full/v21/i11/3337.htm
- DOI: https://dx.doi.org/10.3748/wjg.v21.i11.3337