Copyright
©The Author(s) 2015.
World J Gastroenterol. Mar 21, 2015; 21(11): 3300-3307
Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3300
Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3300
Table 1 Patient characteristics n (%)
Hepatectomy | RFA | P | |
n = 102 | n = 51 | ||
Sex (M/F) | 73/29 | 35/16 | 0.71 |
Age (years) median (range) | 60 (3-79) | 58.5 (35-79) | 0.99 |
Preoperative CEA (ng/mL) median (range) | 4.4 (0.1-202) | 6.5 (0.9-144) | 0.19 |
Size of liver metastases, median (range) | 1.7 (0.2-3.0) | 1.8 (1.0-3.0) | 0.26 |
Number of liver metastasis | |||
Single | 63 (62) | 29 (57) | 0.56 |
Multiple | 39 (38) | 22 (43) | |
Metastasis type | |||
Synchronous | 76 (75) | 33 (65) | 0.21 |
Metachronous | 26 (25) | 18 (35) | |
Location of liver metastasis | |||
Unilobal | 80 (78) | 38 (75) | 0.59 |
Bilobal | 22 (22) | 13 (25) | |
N stage | |||
N0 | 30 (29) | 13 (25) | 0.61 |
N1, N2 | 72 (71) | 38 (75) | |
Location of primary colorectal cancer | |||
Colon | 53 (52) | 29 (57) | 0.57 |
Rectum | 49 (48) | 22 (43) | |
Histological differentiation1 | |||
High grade | 88 (86) | 45 (88) | 0.73 |
Low grade | 14 (14) | 6 (12) | |
Comorbidity | |||
Liver cirrhosis2 | 5 (5) | 6 (12) | 0.18 |
Diabetes mellitus | 20 (20) | 13 (25) | 0.40 |
Hypertension | 29 (28) | 12 (24) | 0.52 |
Cardiovascular disease | 3 (3) | 1 (2) | 0.72 |
Pulmonary disease | 6 (6) | 2 (4) | 0.99 |
Neoadjuvant chemotherapy | |||
Yes | 6 (6) | 5 (10) | 0.30 |
No | 70 (94) | 28 (90) | |
Adjuvant chemotherapy | |||
Yes | 95 (93) | 46 (90) | 0.54 |
No | 7 (7) | 5 (10) |
Table 2 Disease-free survival after surgical treatment with curative intent for colorectal liver metastasis by multivariate analysis by Cox regression proportional hazard model (n = 153)
Factors | Univariate analysis of DFS | Multivariate analysis of DFS | ||
P | HR | 95%CI | P1 | |
Radiofrequency ablation | 0.033 | 1.57 | 1.02-2.41 | 0.040 |
Female sex | 0.890 | |||
Age | 0.270 | |||
CEA (ng/mL) | 0.130 | 1.03 | 0.99-1.01 | 0.480 |
Size (cm) | 0.210 | |||
Multiple | 0.140 | 1.01 | 0.65-1.57 | 0.970 |
Metachronous | 0.089 | 0.75 | 0.45-1.24 | 0.260 |
Bilobal | 0.300 | |||
T22 | 0.130 | 0.55 | 0.18-1.65 | 0.290 |
T32 | 0.090 | 0.78 | 0.41-1.49 | 0.450 |
Lymph node metastasis | 0.003 | 1.94 | 1.14-3.31 | 0.015 |
Adjuvant chemotherapy | 0.810 | |||
Poorly differentiated grade | 0.033 | 1.79 | 1.01-3.18 | 0.049 |
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Citation: Lee H, Heo JS, Cho YB, Yun SH, Kim HC, Lee WY, Choi SH, Choi DW. Hepatectomy
vs radiofrequency ablation for colorectal liver metastasis: A propensity score analysis. World J Gastroenterol 2015; 21(11): 3300-3307 - URL: https://www.wjgnet.com/1007-9327/full/v21/i11/3300.htm
- DOI: https://dx.doi.org/10.3748/wjg.v21.i11.3300