Efficacy of docetaxel combined with oxaliplatin and fluorouracil against stage III/IV gastric cancer

Table 1 Clinical data of the 53 patients

Item	Data
Gender
Male	37
Female	16
Age (yr, mean ± SD)	60.30 ± 9.41
Karnofsky score
90	7
80	20
70	22
60	4
Tumor stage
III	24
IV	29
Pathological type
Poorly differentiated adenocarcinoma	23
Undifferentiated adenocarcinoma	12
Signet-ring cell carcinoma	18
Tumor location
Gastric fundus and cardia	11
Gastric corpus	14
Gastric antrum and pylorus	25
Sclerotic stomach	3
Tumor size (cm), mean ± SD	5.6 ± 1.5
Chemotherapeutic course
1 course	2
2 courses	20
3 courses	16
4 courses	15

Table 2 Main side effects of the 51 patients

Type	Side effects degree				Sum
	I	II	III	IV
Bone marrow suppression
leukopenia	6	9	10	13	38
Thrombocytopenia	5	3	4	1	13
anemia	6	5	2	1	14
Gastrointestinal reactions
Nausea, vomiting	23	14	8	3	48
SGOT/SGPT	5	4	2	0	11
Diarrhea	8	4	0	0	12
Oral mucositis	7	8	4	1	20
Baldness	17	5	3	0	25
Peripheral neuritis	12	1	0	0	13
Urea nitrogen	4	2	0	0	6
Creatinine	3	1	0	0	4