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©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Nov 28, 2014; 20(44): 16433-16442
Published online Nov 28, 2014. doi: 10.3748/wjg.v20.i44.16433
Published online Nov 28, 2014. doi: 10.3748/wjg.v20.i44.16433
Table 1 Target genes in gastric tumours with microsatellite instability
| Gene pathway | Target gene |
| DNA repair/chromatin structure regulation | ATR |
| BLM | |
| CHK1 | |
| MED1 | |
| MRE11 | |
| MSH2 | |
| MSH3 | |
| MSH6 | |
| RAD50 | |
| Signal transduction | DP2 |
| IGFIIR | |
| RIZ | |
| TGF-βRII | |
| Transcriptional regulation | TCF4 |
| E2F4 | |
| microRNA regulation | AGO2 |
| TNRC6A | |
| Cell death | APAF1 |
| BAX | |
| BCL10 | |
| CASPASES | |
| FAS | |
| UVRAG | |
| Other | BHD |
| PAI-1 |
- Citation: Velho S, Fernandes MS, Leite M, Figueiredo C, Seruca R. Causes and consequences of microsatellite instability in gastric carcinogenesis. World J Gastroenterol 2014; 20(44): 16433-16442
- URL: https://www.wjgnet.com/1007-9327/full/v20/i44/16433.htm
- DOI: https://dx.doi.org/10.3748/wjg.v20.i44.16433
