Causes and consequences of microsatellite instability in gastric carcinogenesis

doi:10.3748/wjg.v20.i44.16433

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Nov 28, 2014 (publication date) through Nov 26, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 28, 2014; 20(44): 16433-16442
Published online Nov 28, 2014. doi: 10.3748/wjg.v20.i44.16433

Table 1 Target genes in gastric tumours with microsatellite instability

Gene pathway	Target gene
DNA repair/chromatin structure regulation	ATR
	BLM
	CHK1
	MED1
	MRE11
	MSH2
	MSH3
	MSH6
	RAD50
Signal transduction	DP2
	IGFIIR
	RIZ
	TGF-βRII
Transcriptional regulation	TCF4
Transcriptional regulation	E2F4
microRNA regulation	AGO2
microRNA regulation	TNRC6A
Cell death	APAF1
	BAX
	BCL10
	CASPASES
	FAS
	UVRAG
Other	BHD
Other	PAI-1

Citation: Velho S, Fernandes MS, Leite M, Figueiredo C, Seruca R. Causes and consequences of microsatellite instability in gastric carcinogenesis. World J Gastroenterol 2014; 20(44): 16433-16442
URL: https://www.wjgnet.com/1007-9327/full/v20/i44/16433.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i44.16433