Capsule endoscopy capture rate: Has 4 frames-per-second any impact over 2 frames-per-second?

Table 1 Institutions and patients included

Institution	n
Hospital de Navarra	8
Clinica Universidad de Navarra	5
Hospital Gregorio Marañon	10
Hospital Juan Canalejo	10
Hospital Puerta de Hierro	9
Hospital del Mar	8
Complejo Hospitalario de Toledo	9
Hospital La Fe	10
Hospital General de Valencia	10
Mutua de Tarrassa	10
Total	89

Table 2 PillCam SB2₄ specifications

Physical dimensions	26 mm × 11 mm
Weight	2.89 ± 0.15 g
Number of imaging heads	1
Imager type	CMOS
Image capture rate	4 frames per second
Optical illumination	4 white light emitting diodes with ALC
Field of view	156° - working distance of 4.5 mm
Depth of field	0-30 mm
Mucosa area images at 4.5 mm	Approximately 1100 mm2
Magnification	1.8
Min. detectable object size	0.1 mm
Min. operation time	7 h and 58 min
Max. operation time	9:00 h
Shelf life	10 mo after manufacturing date
Transmitter frequency	434.1 MHz
Battery type	Silver oxide, non-toxic
Storage temperature	0°-30°
Activation	Magnetic, automatic from blister

Table 3 Overall number of lesions and abnormal frames detected n (%)

	Lesions	Frames
	Total	Total
Esophagus	17 (6.6)	132 (4)
Stomach	30 (11.6)	617 (19.1)
Small bowel	193 (75)	2227 (69)
Colon	17 (6.6)	249 (7.7)
Total	257 (100)	3225 (100)

Table 4 Comparative analysis of landmark detection n (%)

	SB24 patients	“SB2-like” patients	P value	K value
Z-line	53 (59.5)	45 (50.6)	NS	0.820
Papilla	7 (7.9)	6 (6.7)	NS	0.917

NS: Not significant.

Table 5 Comparative analysis of frames per landmark n (%)

	SB24		"SB2-like"		P value
	Frames	Mean ± SD	Frames	Mean ± SD
Z-line	616	11.6 ± 20.4	391	8.6 ± 10.6	NS
Papilla	35	5.0 ± 2.0	15	2.5 ± 1.4	< 0.05

NS: Not significant.

Table 6 Comparative analysis of quality of images detected

Quality1	SB24	“SB2-like”	P value
	Mean ± SD	Mean ± SD
	91.94 ± 21.82	88.01 ± 34.87	NS

NS: Not significant.

¹Defined as percent of Z-line detected by the capsule.

Table 7 Lesions detection: Per-patient analysis n (%)

	SB24 patients1	“SB2-like” patients1	P value	K value
Esophagus	15 (23.0)	14 (22.2)	NS	0.9
Stomach	18 (27.7)	18 (28.5)	NS	1.0
Small bowel	59 (90.7)	59 (93.6)	NS	1.0
Colon	11 (16.9)	11 (17.4)	NS	0.9
Total	65 (100)	64 (100)	NS	0.9

¹Patients could be included in more than one category. NS: Not significant.

Table 8 Lesions detection: Per-lesion analysis

	SB24		“SB2-like”		P value
	Lesions	Mean ± SD	Lesions	Mean ± SD
Esophagus	17	0.2 ± 0.4	14	0.1 ± 0.4	NS
Stomach	30	0.3 ± 0.8	30	0.3 ± 0.8	NS
Small bowel	193	2.2 ± 3.1	183	2.1 ± 2.8	NS
Colon	17	0.2 ± 0.6	17	0.2 ± 0.6	NS
Total	257	2.9 ± 3.8	244	2.7 ± 3.5	NS

NS: Not significant.

Table 9 Comparative analysis of frames per lesion

	SB24		“SB2-like”		P value
	Frames	Mean ± SD	Frames	Mean ± SD
Esophagus	132	7.7 ± 9.0	91	6.5 ± 8.7	NS
Stomach	617	20.5 ± 34.2	403	13.4 ± 25.8	NS
Small Bowel	2227	11.5 ± 28.1	1490	8.1 ± 18.1	NS
Colon	249	14.6 ± 18.2	155	9.1 ± 12.4	NS
Total	3225	12.8 ± 15.2	2139	8.7 ± 15.6	NS

NS: Not significant.