Liver resection and metabolic disorders: An undescribed mechanism leading to postoperative mortality

Table 1 Patients characteristics

Patients characteristics	Value
Age (range) (yr)	67.7 (52.1-79)
ASA score: Median (range)	2 (2-3)
Body mass index: Median (range) (kg/m²)	26.1 (20.7-38.6)
Metabolic disorders:
2 disorders	2
3 disorders	4
4 disorders	1
5 disorders	3
Hepatic tumor histopathology:
Hepatocellular carcinoma	4
Colorectal cancer metastasis	3
Intrahepatic cholangiocarcinoma	2
Muco-secreting adenocarcinoma metastasis	1

Table 2 Step by step and timeline (expressed in postoperative day)

Patient	Gender	Increased waist circum-ference	Arterial hyper-tension	Increased fasting glucose	Decreased HDL choleste-rol/increased trigly-cerides	Procedure: Segments and wedge resections3	First day in ICU	First day of jaundice or ascites	First day of renal failure or oliguria/first day of hemofil--tration	First day of inotropes use	Day of death
Patient 11	Male	Yes	Yes	Yes	No / No	V, VI, VII, VIII	1	2	1/6	1	7
Patient 2	Male	Yes	Yes	Yes	Yes/Yes	V, VI, VII, VIII	22	4	2/6	1	10
Patient 3	Male	Yes	Yes	Yes	Yes/Yes	V, VI, VII, VIII	12	6	4/14	14	15
Patient 4	Male	Yes	Yes	Yes	Yes/Yes	Partial IV, V, VI, VII, VIII	3	3	3/9	8	18
Patient 5	Male	No	Yes	Yes	Yes/No	V, VI, VII, VIII	12	7	4/6	4	25
Patient 6	Male	No	Yes	No	Yes/No	V, VI, VII, VIII	7	7	8/no	18	29
Patient 7	Male	Yes	No	No	Yes/Yes	Partial IV, V, VI, VII, VIII	12	2	10/no	1	35
Patient 8	Male	Yes	Yes	No	No/No	II, III, VII	12	3	5/8	1	38
						3 Wedge resections: IV, V, VIII
Patient 9	Male	Yes	Yes	No	Yes/Yes	V, VI, VII, VIII	8	6	8/22	8	43
Patient 10	Lady	No	Yes	Yes	Yes/No	Partial IV, V, VI, VII, VIII,	12	4	4/9	10	52
						Wedge of III
Total or median (range)	9 M/1 F	7	9	6	8/5	N/A	1	4	4 (1-10)/8.5 (6-22)	6	27
							(1-8)	(2-7)		(1-18)	(7-52)

¹A vena cava injury with 3000 mL blood loss;

²Patient admitted in ITU for elective postoperative observation;

³As described in Blumgart LH, Surgery of the Liver, Biliaru Tract, and Pancreas, Fourth Edition. Elsevier/Saunders 2006. No: Patient who did not undergo hemofiltration; HDL: High-density lipoprotein; ICU: Intensive care unit.