Ever-changing endoscopic treatment for early gastric cancer: Yesterday-today-tomorrow

Table 1 Therapeutic outcomes of endoscopic resection for early gastric cancer

Ref.	Published yearcountry	No.(lesion/patients)	Method		En bloc resection (%)		Complete resection (%)		Follow-up(mo/range)	Complications				Recurrence rate(%)				5-yr overall survival rate (%)	5-yr recurrence-free rate (%)
										Bleeding		Perforation
			EMR	ESD	EMR	ESD	EMR	ESD		EMR	ESD	EMR	ESD	Local		Metachronous
Oda et al[15]	2006 Japan	714/655	411	303	56.0	66.3	61.1	73.6	38 (6-60)	0.1	0	1.2	3.6	7.5		NA		99.21	94.42
Oka et al[11]	2006 Japan	1020/896	825	195	42.1	83.1	23.6	83.1	EMR 83.2 ± 34.6 ESD 19.4 ± 9.2	7.6	22.6	4.8	8.7	3.1		NA		NA	NA
Imagawa et al[21]	2006 Japan	196/185		196		93.0		84.0	22.8 (12-46)				6.1	0.0		NA		NA	NA
Chung et al[19]	2009 Korea	534/1000 (dysplasia 466)		534		95.3	87.7		NA		15.6		1.2	NA		NA		NA	NA
Jang et al[22]	2009 Korea	198/198		198		89.7		87.9	30 (9-49)		7.4		2.9	5.1		NA		NA	94.92
Min et al[24]	2009 Korea	346/243	103	243	77.7	95.9	75.7	88.9	29 (4-44)	3.9	5.3	1.9	4.5	0.0		6		NA	NA
Isomoto et al[25]	2009 Japan	589/551		589		94.9		94.7	30 (6-89)		1.8		4.5	0.0		NA		97.1	1003
Goto et al[20]	2009 Japan	276/231		276		96.7		91.7	36 (2-39)		5.1		4.0	0.9		NA		96.2	1003
Nakamoto et al[10]	2009 Japan	202/177	80	122	53.8	94.3	37.5	92.6	54 (12-89)	0		1.6		2.5		NA		100.0	100
Choi et al[8]	2011 Korea	215/215	215				71.2		81 (56-94)					NA		NA		93.6	98.7
Ahn et al[17]	2011 Korea	1370/1244	Absolute Ix						32 (22-48)										98.8-99.02
			355	182	72.4	65.9	94.4	83.0		1.4	0.8	0.3	1.2	1.5	0.5	6.1	2.2	95.8-95.3
			Expanded Ix
			497	336	96.8	95.5	97.8	91.1		1.6	2.1	1.6	2.4	1.6	0.8	13.7	4.0	96.8	98.52
Catalano et al[29]	2009 Italy	48/45	36	12	72.0	92.0	56.0	92.0	31 (12-71)	8.0	8	0.0	8.0	0.0		NA		NA	NA
Dinis-Ribeiro et al[30]	2009 Portugal	19/19		19		79.0		89.0	10		5		0.0	0.0		NA		NA	NA
Probst et al[34]	2010 Germany	91/83 (EGC 66)	1	85	100.0	88.2	90.0	68.6	27 (1-71)	3.5		1.2		6.6		NA		NA	90.12
Schumacher et al[36]	2012 Germany	30/30 (EGC 21)		30		90.0		64.3	22		4		6.0	10.7		NA		NA	NA
Repici et al[35]	2013 Italy	42/42 (EGC 10)		42		100.0		92.8	19 (9-53)		7.1		0.0	5.0		NA		NA	NA
Chaves et al[32]	2013 Brazil	62/61 (EGC 55)		62		82.2		77.4	11.3 (1-30)		0		4.8	0.0		3.5		NA	NA

¹3-year overall survival rate;

²3-year recurrence free rate;

³5-year disease specific survival. EGC: Early gastric cancer; EMR: Endoscopic mucosal resection; ESD: Endoscopic submucosal dissection; NA: Not applicable; Ix: Indication.