Magnetic imaging-assisted colonoscopy vs conventional colonoscopy: A randomized controlled trial

Table 1 Patient characteristics n (%)

Characteristics	Conventional colonoscopy(n = 122)	Magnetic imaging colonoscopy(n = 131)	Total(n = 253)
Age (yr, range)	58.2 (18-82)	57.7 (19-86)	57.9 (18-86)
Gender-male	63 (51.6)	68 (51.9)	131 (51.8)
Previous colonoscopy	77 (63.1)	66 (50.4)	143 (56.5)
Prior abdo or pelvic surgery	19 (15.6)	26 (19.9)	45 (17.8)
Indication
Screening or polyp follow-up	71 (58.2)	79 (60.3)	150 (59.3)
GI bleeding	13 (10.7)	23 (17.6)	36 (14.2)
Anemia or FOBT+	7 (5.7)	10 (7.6)	17 (6.7)
Diarrhea	5 (4.1)	11 (8.4)	16 (6.3)
IBD	8 (6.6)	4 (3.1)	12 (4.7)
Other	18 (14.8)	4 (3.1)	22 (8.7)

GI: Gastrointestinal; FOBT: Fecaloccultbloodtest; IBD: Inflammatory bowel disease.

Table 2 Endoscopic outcomes

Endoscopic outcomes	Conventional colonoscopy(n = 122)	Magnetic imaging colonoscopy(n = 131)	Total(n = 253)	P value
Cecal intubation n (%)	121 (99.2)	131 (100)	252 (99.6)	0.30
TI intubation n (%)	42 (34.4)	46 (35.1)	88 (34.8)	0.91
Distance to cecum (cm)	83 (53–130)	82.4 (49–150)	82.7 (49–150)	0.71
Time-to-cecum (min)	7.2 (2-29.5)	6.5 (1.2-28)	6.9 (1.2-29.5)	0.18
Total procedure time (min)	16.7 (8.1-36)	15.7 (5.7-40)	16.2 (5.7-40)	0.19
Polyp detection rate	51.60% (0.43, 0.61)	46.60% (0.38, 0.55)	49.0%	0.42
Meanpolyps (range)	1.7 (1-7)	1.9 (1-8)	1.8 (1-8)	0.36
Quality of bowel prep
Excellent	21.3%	29.8%	25.7%
Acceptable	49.2%	43.5%	46.3%
Fair	25.4%	24.4%	24.9%
Poor	4.1%	2.3%	3.2%
Procedures self-rated as “difficult”n (%)	25 (20.5)	36 (27.5)	61 (24.1)	0.19
Sedation, mean doses (range)
Midazolam (mg)	5.8 (3-15)	5.5 (2-15)	5.7 (2-15)	0.31
Fentanyl (mcg)	86.3 (50-150)	83.2 (50-150)	84.7 (50-150)	0.29

TI: Terminal ileum.

Table 3 Patient experience outcomes

Score	Conventional colonoscopy(n = 122)	Magnetic imaging colonoscopy(n = 131)	Total(n = 253)	P value
Pain score	0.85 (0.1-8.4)	1.03 (0.1-10)	0.94 (0.1-10)	0.41
Pretest pain score	2.2 (0.1-8.5)	2.9 (0.1-9)	2.5 (0.1-9)	0.02
Pain difference	-1.3	-1.8	-1.6	0.14
Sedation score	8.5 (4.5-17)	8.2 (4-21)	8.3 (4-21)	0.34

Table 4 Subgroup of self-rated “difficult” colonoscopy procedures

Colonoscopy procedures	Conventional colonoscopy(n = 25)	Magnetic imaging colonoscopy(n = 36)	Total(n = 61)	P value
Time-to-cecum (min)	13.4	10.10	11.50	0.01
	(6.7-29.5)	(3.8-28)	(3.8-29.5)
Distance to cecum (cm)	91.20	85.70	88	0.30
	(68-130)	(49-150)	(49-150)
Sedation score	9.54	9.08	9.27	0.61
	(5-17)	(5-21)	(5-21)
Pain score	1.48	1.15	1.28	0.53
	(0.1-8.4)	(0.1-7.9)	(0.1-8.4)
Pain difference	-1.05	-1.50	-1.32	0.54
	(-6.8-3.3)	(-7.8-4.9)	(-7.8-4.9)