Surgical management of colonic diverticular disease: Discrepancy between right- and left-sided diseases

Table 1 Diverticular disease distribution n (%)

Site	Number of cases according to study periods
	1982.3-1993.6[12]	1993.7-1999.9[13]	1999.10-2010.7
Right colon	18 (75.0)	13 (48.1)	40 (51.9)
Left colon	3 (12.5)	11 (40.7)	37 (48.1)
Bilateral	3 (12.5)	3 (11.1)	0 (0)
Total	24	27	77

Table 2 Clinical characteristics according to the site of diverticular disease n (%)

Variables	Right (n = 40)	Left (n = 37)	P value
Age (yr)1	50.9 ± 15.0	64.0 ± 14.0	< 0.01
Gender (M/F)	29/11	20/17	0.09
Disease category			< 0.01
Diverticular bleeding	9 (22.5)	0 (0)
Uncomplicated diverticulitis	8 (20.0)	4 (10.8)
Complicated diverticulitis	23 (57.5)	33 (89.2)
Smoking	14 (35.9)	8 (21.6)	0.19
Alcohol consumption	21 (52.5)	7 (18.9)	< 0.01
BMI1	23.8 ± 2.5	23.2 ± 3.0	0.35
Fever	14 (35.0)	8 (21.6)	0.19
Leukocytosis	14 (35.0)	17 (45.9)	0.33
Multiple sites	22 (55.0)	28 (75.7)	0.06

¹Date are expressed as mean ± SD. BMI: Body mass index.

Table 3 Postoperative outcomes according to the site of diverticular disease n (%)

Variables	Right (n = 40)	Left (n = 37)	P value
Operation time (min)1	122.4 ± 41.6	141.9 ± 51.1	0.07
Combined resection	2 (5.0)	8 (21.6)	0.04
Postoperative hospital stay (d)1	10.6 ± 8.1	21.3 ± 10.2	0.01
Complications	11 (27.5)	19 (51.4)	0.03
Mortality	0 (0)	4 (10.8)	< 0.05

¹Date are expressed as mean ± SD.

Table 4 Postoperative outcomes of diverticulitis according to Hinchey’s criteria n (%)

	No peritonitis(n = 43)	Peritonitis(n = 25)	P value
Right/left	25/18	6/19	0.01
Emergency	4 (9.3)	24 (96.0)	< 0.01
Two-stage operation	1 (2.3)	20 (80.0)	< 0.01
Operation time (min)1	125.1 ± 46.3	144.8 ± 44.2	0.09
Complications	8 (18.6)	19 (76.0)	< 0.01
Mortality	0 (0)	4 (16.0)	0.02

¹Date are expressed as mean ± SD. The no peritonitis group includes patients with uncomplicated diverticulitis or complicated diverticulitis classified as Hinchey grade 1 or 2. The peritonitis group includes patients with complicated diverticulitis classified as Hinchey grade 3 and 4.

Table 5 Postoperative outcomes of diverticulitis according to the preoperative immune status n (%)

	Immunocompetent (n = 60)	Immunocompromised (n = 8)	P value
Right/left	29/31	2/6	0.28
Symptom duration (d)1	238.2 ± 66.3	7.0 ± 1.8	< 0.01
Hinchey grade 3, 4	19 (31.7)	6 (75.0)	0.04
Emergency operation	22 (36.7)	6 (75)	0.06
Two-stage operation	14 (23.3)	7 (87.5)	< 0.01
Complications	22 (36.7)	5 (62.5)	0.25
Mortality	0 (0)	4 (50.0)	< 0.01

¹Date are expressed as mean ± SD.