Treatment of rectal cancer by transanal endoscopic microsurgery: Experience with 425 patients

doi:10.3748/wjg.v20.i28.9556

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

World J Gastroenterol. Jul 28, 2014; 20(28): 9556-9563
Published online Jul 28, 2014. doi: 10.3748/wjg.v20.i28.9556

Table 1 Main patient characteristics n (%)

Variables
Preoperative stage T1 (120 patients)
Sex, male	79 (65.0)
Age (yr)
[median, (25^th p-75^th p)]	68 (60-74)
Follow-up (mo)
[median, (25^th p-75^th p)]	82 (48-144)
Operative time (min)
[median, (25^th p-75^th p)]	70 (60-90)
Hospital stay (d)
[median, (25^th p-75^th p)]	2 (2-3)
Definitive histology [n (%)]
pT₁	110 (91.7)
pT₂	10 (8.3)
Stage T2 before radiotherapy (185 patients)
Sex, male	120 (64.9)
Age (yr)
[median, (25^th p-75^th p)]	68 (60-74)
Follow-up (mo)
[median, (25^th p-75^th p)]	53 (32-125)
Operative time (min)
[median, (25^th p-75^th p)]	70 (60-120)
Hospital stay (d)
[median, (25^th p-75^th p)]	4 (3-5)
Post-radiotherapy stage
pT₀	63 (34.1)
pT₁	25 (13.5)
pT₂	97 (52.4)
Stage T3 before radiotherapy (120 patients)
Sex, male	70 (58.3)
Age (yr)
[median, (25^th p-75^th p)]	69.5 (62.5-75)
Follow-up (mo)
[median, (25^th p-75^th p)]	70 (42-133.5)
Operative time (min)
[median, (25^th p-75^th p)]	90 (60-120)
Hospital stay (d)
[median, (25^th p-75^th p)]	3 (3-4)
Postradiotherapy stage
pT₀	17 (14.2)
pT₁	13 (10.8)
pT₂	49 (40.8)
pT₃	41 (34.2)

Table 2 Cumulative probability of recurrence at the end of follow-up

Cumulative probability	Value
Preoperative stage T1 (120 patients)
Follow-up: 253 mo	Patients with stage T1 before radiotherapy
Probability of death (95%CI)	0.47 (0.21-0.64)
Events (n)	22
Stage T2 before radiotherapy (185 patients)
Follow-up: 255 mo	Patients with stage T2 lesions before radiotherapy
Probability of local recurrence or	0.13 (0.08-0.18)
metastasis (95%CI)	0.13 (0.08-0.18)
Events (n)	21
Probability of cancer-specific death (95%CI)	0.07 (0.03-0.12)
Events (n)	10
Probability of death (95%CI)	0.50 (0.21-0.68)
Events (n)	33
Stage T3 before radiotherapy (120 patients)
Follow-up: 239 mo	Patients with stage T3 lesions before radiotherapy
Probability of local recurrence or	0.12 (0.05-0.17)
metastasis (95%CI)	0.12 (0.05-0.17)
Events (n)	13
Probability of cancer-specific death (95%CI)	0.11 (0.06-0.17)
Events (n)	11
Probability of death (95%CI)	0.55 (0.33-0.70)
Events (n)	33

Citation: Guerrieri M, Gesuita R, Ghiselli R, Lezoche G, Budassi A, Baldarelli M. Treatment of rectal cancer by transanal endoscopic microsurgery: Experience with 425 patients. World J Gastroenterol 2014; 20(28): 9556-9563
URL: https://www.wjgnet.com/1007-9327/full/v20/i28/9556.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i28.9556