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Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Jul 28, 2014; 20(28): 9392-9404
Published online Jul 28, 2014. doi: 10.3748/wjg.v20.i28.9392
Table 1 Increased expression patterns for Pim kinases in various types of malignancies
Tumor subtypePim-1Pim-2Pim-3
Solid tumor
Pancreatic cancer+ND+
Colon carcinoma+ND+
Gastric cancer+ND+
Hepatocellular carcinoma+++
Prostate adenocarcinoma+++
Bladder carcinoma+NDND
Squamous cell carcinoma of head and neck+NDND
Nasopharyngeal carcinomaNDND+
Oral squamous cell carcinoma+NDND
Liposarcoma+NDND
Ewing’s sarcomaNDND+
Hematological malignancies
Acute myeloid leukemiaND+ND
B Cell chronic lymphocytic leukemiaND+ND
Primary mediastinal large B cell lymphoma+NDND
Mantle cell lymphoma++ND
Diffuse large B cell lymphoma++ND
Burkitt’s lymphoma+NDND