Modern approach to the clinical management of non-alcoholic fatty liver disease

doi:10.3748/wjg.v20.i26.8341

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Jul 14, 2014 (publication date) through Nov 23, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 14, 2014; 20(26): 8341-8350
Published online Jul 14, 2014. doi: 10.3748/wjg.v20.i26.8341

Table 1 Major proposed interventions for nonalcoholic fatty liver disease

Lifestyle intervention

Calorie restriction

Mediterranean diet

Exercise

Medication

Weight loss drugs

Orlistat

Sibutramine

Antidiabetics

Metformin

Pioglitazone

DPP IV inhibitors

GLP-1 receptors agonists

Antioxidants

Vitamin E

Statins

Pravastatin

Pitavastatin

Atorvastatin

Rosuvastatin

PUFA

Vitamin D

UDCA

Probiotics

Berberine

Silymarin

Silybin

Bariatric surgery

Table 2 Main targets of intervention in nonalcoholic fatty liver disease

Overweight and obesity

Sedentary lifestyles

Insulin resistance

Oxidative stress

Atherogenic dyslipidemia

Vitamin D deficiency

Hepatocyte protection

Cardiovascular risk

Treatment of comorbidities

Mitochondrial dysfunction

Citation: Ben MD, Polimeni L, Baratta F, Pastori D, Loffredo L, Angelico F. Modern approach to the clinical management of non-alcoholic fatty liver disease. World J Gastroenterol 2014; 20(26): 8341-8350
URL: https://www.wjgnet.com/1007-9327/full/v20/i26/8341.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i26.8341