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Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Jul 14, 2014; 20(26): 8341-8350
Published online Jul 14, 2014. doi: 10.3748/wjg.v20.i26.8341
Table 1 Major proposed interventions for nonalcoholic fatty liver disease
Lifestyle intervention
Calorie restriction
Mediterranean diet
Exercise
Medication
Weight loss drugs
Orlistat
Sibutramine
Antidiabetics
Metformin
Pioglitazone
DPP IV inhibitors
GLP-1 receptors agonists
Antioxidants
Vitamin E
Statins
Pravastatin
Pitavastatin
Atorvastatin
Rosuvastatin
PUFA
Vitamin D
UDCA
Probiotics
Berberine
Silymarin
Silybin
Bariatric surgery
Table 2 Main targets of intervention in nonalcoholic fatty liver disease
Overweight and obesity
Sedentary lifestyles
Insulin resistance
Oxidative stress
Atherogenic dyslipidemia
Vitamin D deficiency
Hepatocyte protection
Cardiovascular risk
Treatment of comorbidities
Mitochondrial dysfunction