Capsule endoscopy in patients refusing conventional endoscopy

Table 1 Main studies published on PillCam Colon in esophageal varices

Ref.	n	S	E	Accuracy of treatment1
Eisen et al[17], 2006	32	100%	89%	NA
de Franchis et al[18], 2008	288	88%	84%	91%
Lapalus et al[19], 2009	120	77%	86%	92%
Ishiguro et al[21], 2012	29	95%	84%	85%

¹Accuracy for indicated prophylactic treatment.

Table 2 Results of main colon trials using PillCam Colon 1

PillCam Colon C1	Year	n	S	E	PPV	NPV
Results for polyps (any size)
Eliakim et al[35]	2006	91	69%	81%	74%	78%
Schoofs et al[36]	2006	41	76%	64%	83%	54%
Van Gossum et al[34]	2009	328	64%	84%	60%	86%
Results for significant polyps (> 6 mm or > 3 polyps > 3 mm)
Eliakim et al[35]	2006	91	63%	94%	67%	91%
Schoofs et al[36]	2006	41	60%	73%	46%	83%
Van Gossum et al[34]	2009	328	64	84

PPV: Positive predictive value; NPV: Negative predictive value.

Table 3 Results of main colon trials using PillCam Colon 2

PillCam Colon C2	Year	n	S	E
Results for significant polyps (> 6 mm or > 3 polyps > 3 mm)
Eliakim et al[40]	2009	98	89%	84%
Spada et al[41]	2011	109	76%	64%
Results for significant polyps (> 10 mm)
Eliakim et al[40]	2009	98	88%	89%
Spada et al[41]	2011	109	88%	95%

Table 4 Bowel preparation schedule

Schedule		Intake
Day-2		Sennosides 80-160 mg
Day-1	All day	Clear liquid diet
	Evening	2 L PEG
		or
		1 L PEG + ascorbic acid
Exam Day	Morning	2 L PEG
		or
		1 L PEG + ascorbic acid
	Approximately 10 am	Capsule Ingestion
	1st Boost	30 mL NaP and 1 L water
	Small bowel detection	or
		0.5 L PEG
	2nd boost	15 mL NaP and 0.5 L water
	3 h after 1st boost	or
		0.5 L PEG
	Suppository	10 mg bisacodyl
	2 h after 2nd boost