Noninvasive diagnosis of cirrhosis: A review of different imaging modalities

Table 1 Diagnostic performance of transient elastography for the diagnosis of cirrhosis in different chronic liver disease from different etiology, data from meta-analysis

Meta-analysis	No. of studies	Etiology	Cut-off (kPa)	Sensitivity	Specificity	AUROC
Bota et al[53]	13	Various	-	89%	87%	-
Shaheen et al[107]	4	HCV	12.5	86%	93%	0.95
Talwalkar et al[108]	9	Various	-	87%	91%	-
Friedrich-Rust et al[109]	50	Various	-	-	-	0.94
Tsochatzis et al[110]	40	HCV	15 ± 4.1	83%	89%	-
Adebajo et al[111]	5	HCV	-	98%	84%	-
Stebbing et al[112]	22	Various	15.08	84.45%	94.69%	-
Abd El Rihim et al[113]	23	Various	-	83.40%	92.40%	-
Chon et al[114]	18	HBV	11.7	84.60%	81.50%	0.929

AUROC: Area under receiver operating characteristic; HCV: Hepatitis C virus; HBV: Hepatitis B virus.

Table 2 Diagnostic performance of acoustic radiation force impulse for the diagnosis of cirrhosis in different chronic liver disease from different etiology, data from main published meta-analysis

Meta-analysis	No. of studies	Etiology	Cut-off (m/s)	Sensitivity	Specificity	AUROC
Bota et al[53]	13	Various	-	87%	87%	-
Friedrich-Rust et al[57]	9	Various	1.80	-	-	0.93
Nierhoff et al[115]	36	Various	1.87	-	-	0.91

AUROC: Area under receiver operating characteristic.