Helicobacter pylori eradication in patients with chronic immune thrombocytopenic purpura

Table 1 Prevalence of Helicobacter pylori in patients with immune thrombocytopenic purpura (n = 36)

ITP Patients	n (%)
H. pylori positive	17 (47.2)
H. pylori negative	19 (52.8)
Total	36 (100)

ITP: Immune thrombocytopenic purpura; H. pylori: Helicobacter pylori.

Table 2 Comparison of platelet count at 6 wk follow up between Helicobacter pylori eradicated patients and Helicobacter pylori negative patients (n = 32)

Groups	n	Platelet count (mean ± SD)/mm3	P value1	CI
H. pylori eradicated	13		0.003	-89230.8 - -20000
Baseline count		88615.38 ± 30117.93
Count at 6 wk		143230.77 ± 52437.51
H. pylori negative	19		0.001	-104526 - -2736.8
Baseline count		71000.00 ± 33216.46
Count at 6 wk		137631.58 ± 74364.13

¹Unpaired t test. H. pylori: Helicobacter pylori.

Table 3 Comparison of platelet count at 3 mo follow up between Helicobacter pylori eradicated patients and Helicobacter pylori negative patients (n = 35)

Groups	n	Platelet count (mean ± SD)/mm3	P value1	CI
H. pylori eradicated	16		0.0001	-100118.68 - -36256.32
Baseline count		84375.00 ± 33372.39
Count at 3 mo		152562.50 ± 52892.3
H. pylori negative	19		0.0050	-91249.09 - -17908.79
Baseline count		71000.00 ± 33216.46
Count at 3 mo		125578.95 ± 71472.1

¹Unpaired t test. Post salvage therapy 3 patients added to H. pylori eradication Group. H. pylori: Helicobacter pylori.

Table 4 Comparison of platelet count at 6 mo follow up between Helicobacter pylori eradicated patients and Helicobacter pylori negative patients (n = 35)

Groups	n	Platelet count (mean ± SD)/mm3	P value1	CI
H. pylori eradicated	16		0.0001	-93120.40--38504.60
Baseline count		84375.00 ± 33372.39
Count at 6 mo		150187.50 ± 41796.68
H. pylori negative	19		0.6840	-36862.56-24441.51
Baseline count		71000.00 ± 33216.46
Count at 6 mo		77210.53 ± 56892.28

¹Unpaired t test. H. pylori: Helicobacter pylori.

Table 5 Comparison of platelet response in patients with successful eradication and Helicobacter pylori negative patients

Groups	n	Response		P value1	CI
		Yes (CR/PR)	No (NR)
H. pylori eradicated	16	16 (13/3)	0	0.002	0.2835–0.6308
H. pylori negative	19	10 (5/5)	9

¹Unpaired t test. H. pylori: Helicobacter pylori.