Five-year follow-up of 263 cases of functional bowel disorder

Table 1 Baseline clinic data for each functional bowel disorder

FBD	n (%)	Age (yr)(mean ± SD)	Gender (F/M)	Residence (urban/rural)	Duration of FBD
IBS	134 (47.1)	45.44 ± 10.32	63/71	68/66	6 mo-20 yr
Functional abdominal bloating	24 (9.1)	43.17 ± 11.86	10/14	13/11	6 mo-17 yr
Functional constipation	29 (11.0)	46.59 ± 13.22	10/19	12/17	6 mo-20 yr
Functional diarrhea	66 (25.1)	46.56 ± 9.34	41/25	34/32	6 mo-20 yr
Unspecified FBD	10 (3.8)	41.90 ± 13.40	4/6	4/6	6 mo-10 yr

No differences were found in age, gender, place of residence (urban or rural) or duration of functional bowel disorder (FBD) among groups (all P > 0.05). F: Female; M: Male; IBS: Irritable bowel syndrome.

Table 2 Details of patient deaths during follow-up

Details	n/N (%)
Age (yr), mean ± SD
Baseline	66.60 ± 6.84a
Death	70.40 ± 5.86
Gender
Female	2/135 (1.48)
Male	3/128 (2.34)
Residence
Urban	3/133 (2.26)
Rural	2/130 (1.54)
Cause of death
Cardiovascular	2
Gastric cancer	1
Colonic cancer	2
Diagnosis at baseline
IBS	1/134 (0.75)
Functional abdominal bloating	1/24 (4.17)
Functional constipation	2/29 (6.90)
Functional diarrhea	1/66 (1.52)
Unspecified FBD	0/10 (0)

^aP < 0.001 vs baseline in patients who survived; no differences in survival were found between genders, places of residence or functional bowel disorder (FBD) groups (all P > 0.05). IBS: Irritable bowel syndrome.

Table 3 Details of organic bowel diseases observed in functional bowel disorder patients

Details	n/N (%)
Colonic cancer
Age (yr), mean ± SD
Baseline	60.33 ± 1.53b
Cancer observed	63.67 ± 2.08
Gender
Female	1/135 (0.74)
Male	2/128 (1.56)
Residence
Urban	2/133 (1.50)
Rural	1/130 (0.77)
Diagnosis at baseline
IBS	0/134 (0)
Functional abdominal bloating	0/24 (0)
Functional constipation	2/29 (6.70)e
Functional diarrhea	1/66 (1.52)
Unspecified FBD	0/10 (0)
Colonic polyps
Age (yr), mean ± SD
Baseline	54.50 ± 6.47c
Polyps observed	57.83 ± 6.52
Gender
Female	2/135 (1.48)
Male	4/128 (3.13)
Residence
Urban	2/133 (1.50)
Rural	4/130 (3.08)
Diagnosis at baseline
IBS	5/134 (3.62)
Functional abdominal bloating	0/24 (0)
Functional constipation	0/29 0()
Functional diarrhea	1/66 (1.52)
Unspecified FBD	0/10 (0)

^bP < 0.01 vs baseline in patients without colonic cancer;

^cP < 0.05 vs baseline in patients without colonic polyps;

^eP < 0.05 vs IBS but not other FBD groups; no differences in the incidence of colonic cancer or polyps were found between genders and places of residence and no differences in the incidence of colonic polyps were found among FBD groups (all P > 0.05). FBD: Functional bowel disorder; IBS: Irritable bowel syndrome.