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©2013 Baishideng Publishing Group Co.
World J Gastroenterol. Feb 14, 2013; 19(6): 889-896
Published online Feb 14, 2013. doi: 10.3748/wjg.v19.i6.889
Published online Feb 14, 2013. doi: 10.3748/wjg.v19.i6.889
Characteristic | |
Sex (female) | 9 |
Age, yr (mean ± SD) | 56.2 ± 9.7 |
Reason for NSAID therapy | |
Rheumatoid arthritis | 2 |
Osteoarthritis | 8 |
Medication use | |
Anti-hypertensive agents | 3 |
Anti-diabetic agents | 2 |
Low dose aspirin | NA |
Statin | 2 |
Subject No. | First tertile | Second tertile | Third tertile | Total LIS score |
NSAID | ||||
1 | 429 | 3040 | 1404 | 3040 |
2 | 225 | 450 | 0 | 450 |
3 | 1630 | 225 | 225 | 1630 |
4 | 1462 | 204 | 1462 | 1462 |
5 | 247 | 247 | 0 | 247 |
6 | 1104 | 654 | 562 | 1104 |
7 | 1312 | 712 | 135 | 1312 |
8 | 361 | 0 | 0 | 361 |
9 | 1068 | 1068 | 225 | 1068 |
10 | 1690 | 393 | 135 | 1690 |
NSAID + mesalazine | ||||
1 | 900 | 1208 | 1237 | 1208 |
2 | 1462 | 165 | 0 | 1462 |
3 | 247 | 0 | 247 | 247 |
4 | 1068 | 339 | 1012 | 1068 |
5 | 112 | 0 | 0 | 112 |
6 | 1068 | 900 | 225 | 1068 |
7 | 1068 | 1068 | 233 | 1068 |
8 | 225 | 225 | 135 | 225 |
9 | 1104 | 0 | 0 | 1104 |
10 | 1690 | 1554 | 1104 | 1690 |
Inclusion | After mesalazine gran therapy | P value | |
Total Lewis Index Score | 1236.4 ± 821.9 | 925.2 ± 543.4 | 0.271 |
1st tertile | 952.8 ± 584.9 | 894.4 ± 534.3 | 0.569 |
2nd tertile | 699.3 ± 877.9 | 545.9 ± 580.9 | 0.649 |
3rd tertile | 415.3 ± 561.5 | 319.3 ± 403.3 | 0.247 |
Ulcers with a diameter of > 3 mm, n | |||
1st tertile | 8 | 7 | 1.000 |
2nd tertile | 8 | 6 | 0.625 |
3rd tertile | 3 | 4 | 1.000 |
Gastric transit time (min) | 43.8 ± 32 | 49.8 ± 35.6 | 0.470 |
Small bowel transit time (min) | 261.9 ± 108 | 250.9 ± 93.9 | 0.470 |
Cleanliness score | 1.3 ± 0.67 | 1.4 ± 0.69 | 0.345 |
Hemoglobin | 131.1 ± 5.8 | 127.1 ± 7.8 | 0.103 |
- Citation: Rácz I, Szalai M, Kovács V, Regőczi H, Kiss G, Horváth Z. Mucosal healing effect of mesalazine granules in naproxen-induced small bowel enteropathy. World J Gastroenterol 2013; 19(6): 889-896
- URL: https://www.wjgnet.com/1007-9327/full/v19/i6/889.htm
- DOI: https://dx.doi.org/10.3748/wjg.v19.i6.889