Brief Article
Copyright ©2013 Baishideng Publishing Group Co.
World J Gastroenterol. Dec 28, 2013; 19(48): 9328-9333
Published online Dec 28, 2013. doi: 10.3748/wjg.v19.i48.9328
Table 1 Baseline characteristics of hepatocellular carcinoma cases
HCV Ab(+), HCV RNA(+) (n = 108)HCV Ab(+) (n = 77)P value
Age (yr), mean ± SD60.88 ± 8.659.42 ± 7.40.88
Males73.10%67.53%0.32
African American75.90%72.70%0.22
n = 70n = 520.20
BMI (kg/m2)29.56 ± 6.1127.88 ± 5.2
HIV coinfection10.20%7.60%0.16
Heavy alcohol use37.03%48.05%0.04
Table 2 Comparison of variables in cases and controls
CHC with HCC (n = 185)CHC without HCC (n = 356)P value
Age (yr), mean ± SD60.3 ± 9.7159.72 ± 9.2
Males70.80%71.10%
Race AA74.60%78.70%
CAU21.60%18.50%
Other3.80%2.80%
BMI (kg/m2)n = 122n = 320
28.8 ± 6.0127.26 ± 5.9
Albuminn = 178n = 289
2.67 ± 0.73.88 ± 0.6< 0.01
PT (s)n = 171n = 242
16.69 ± 8.611.57 ± 2.5< 0.01
AFP (ng/mL)n = 163n = 284
99035.1 ± 263605.521.12 ± 90.4
Plateletsn = 172n = 337
176.5 ± 127202.98 ± 83.40.04
ALT (IU/L)n = 166n = 345
263.8 ± 518.278.19 ± 58.3< 0.01
AST (IU/L)n = 160n = 324
283.8 ± 63.575.2 ± 55.9< 0.01
HIV co-infection8.10%2.50%0.05
Alcohol
Mild29.7%27.50%NS
Heavy41.60%27%0.03
Non drinkers10.80%31.70%< 0.01
Table 3 Univariate analysis predicting the following
OR (95%CI)P value
HCC in patients with CHC
HBcAb(+)1.90 (1.28-3.04)0.02
HBsAb(-) and HBcAb(+)3.24 (2.28-4.62)< 0.01
HCC in cirrhotic patients with CHC
HBcAb(+)1.54 (1.18-2.54)0.02
HBsAb(-) and HBcAb(+)2.14 (1.68-3.82)0.01
HCC in patients with CHC when controlled for covariates1
HBcAb(+)1.84 (1.22-3.08)0.01
HBsAb(-) and HBcAb(+)2.98 (2.12-5.08)< 0.01
HCC in cirrhotic patients with CHC when controlled for covariates1
HBcAb(+)1.66 (1.22-3.24)0.01
HBsAb(-) and HBcAb(+)2.10 (1.72-4.04)< 0.01
HCC in cirrhotic African American patients with CHC when controlled for covariates1
HBcAb(+)2.08 (1.42-3.6)< 0.01
HBsAb(-) and HBcAb(+)2.58 (1.82-4.44)< 0.01