Liver diseases in pregnancy: Liver transplantation in pregnancy

Table 1 Summary of important fetal and maternal outcomes in liver transplant recipients from selected publications

Author, reference, number of pregnancies	Live birth rate (%)	Preterm (%)	Graft dysfunction (%)	Cesarean section rate (%)	Spontaneous abortions (%)	Low birth weight < 2500 g (%)	Maternal/neonatal deaths (%)
Nagy et al[12], n = 38	63	29	17	46	NA	17	17/0
Jain et al[13], n = 49	100	4	25	47	0	9	10/6
Armenti et al[14], n = 205	73	35	7	35	19	34	/0
Christopher et al[15], n = 71	71	NA	17	40	19	20	4/0
Dei Malatesta et al[16], n = 285	78	31	10	43	NA	23	/4
Sibanda et al[17], n = 16	69	50	NA	62	13	57	NA
Coffin et al[18], n = 206	70	27	5	38	5	NA	0/6
Jabiry-Zieniewicz et al[19], n = 39	100	31	8	80	0	20	/0
Dashpande et al[9], n = 450	76.9	39.4	NA	44.6	6.2 (including intrauterine fetal death)	NA	NA
Alvaro et al[10], n = 30	66.6	NA	10	42	26.6	NA	0/6

NA: Not available.

Table 2 Food and drug administration pregnancy categories of common immunosuppressive therapy

Medicine	Pregnancy category
Corticosteroids	B
Azathioprine	D
Cyclosporin	C
Mycophenolate mofetil	D
Tacrolimus	C
Sirolimus	C